Results 71 to 80 of about 1,700,137 (238)

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Sialome of a generalist lepidopteran herbivore: identification of transcripts and proteins from Helicoverpa armigera labial salivary glands.

PLoS ONE, 2011
Although the importance of insect saliva in insect-host plant interactions has been acknowledged, there is very limited information on the nature and complexity of the salivary proteome in lepidopteran herbivores.
Maria de la Paz Celorio-Mancera, Juliette Courtiade, Alexander Muck, David G Heckel, Richard O Musser, Heiko Vogel   +5 more
doaj   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Lectin microarray analysis of salivary gland glycoproteins from arboviral vector Aedes aegypti and malaria vector Anopheles stephensi

Journal of Vector Borne Diseases
Background & objectives: Salivary gland proteins but not glycoconjugates have been previously studied in mosquito vectors of human diseases. Glycoconjugates from salivary gland-derived proteins from human-feeding tick vectors can elicit hypersensitivity ...
Ranjan Ramasamy, Xi Chen, Jian Zhang, Kokila Sivabalakrishnan, Sivasingham Arthiyan, Sinnathamby N Surendran   +5 more
doaj   +1 more source

iTRAQ-based quantitative analysis of age-specific variations in salivary proteome of caries-susceptible individuals

Journal of Translational Medicine, 2018
Background Human saliva is a protein-rich, easily accessible source of potential biomarkers for the diagnosis of oral and systemic diseases. However, little is known about the changes in salivary proteome associated with aging of patients with dental ...
Kun Wang, Xiuqing Wang, Sainan Zheng, Yumei Niu, Wenyue Zheng, Xi Qin, Zhongcheng Li, Junyuan Luo, Wentao Jiang, Xuedong Zhou, Wei Li, Linglin Zhang   +11 more
doaj   +1 more source

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

Advanced Science, EarlyView.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta, Zhicheng Jin, Mari Adachi, Lubna Amer, Natalia O. Tjokro, Diego F. Trujillo, Jan Potempa, Anthony J. O'Donoghue, Casey Chen, Jesse V. Jokerst   +9 more
wiley   +1 more source

Salivary-gland ultrasonography grade correlates with salivary flow and histology.

, 2016
SGUS, salivary gland ultrasonography; UWSF, unstimulated whole salivary flow. The total SGUS grade obtained by summing the grades of the two parotid and two submandibular glands can range from 0 to 16.
Jacques-Olivier Pers (356421), Alain Saraux (356420), Valérie Devauchelle-Pensec (3134643), Divi Cornec (795436), Eric Hachulla (164861), Sebastian Costa (3134646), Thierry Marhadour (3134649), Pierre-Yves Hatron (391760), Vincent Goeb (415345), Sandrine Jousse-Joulin (795429), Olivier Vittecoq (408284), Pascale Marcorelles (375974), Emmanuel Nowak (795437), Jean-Marie Berthelot (795430)   +13 more
core   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Proteins

, 2004
Solvation energy calculation is one of the main difficulties for the estimation of protein-ligand binding free energy and the correct scoring in docking studies.
Zhou, JJ, Wang, Q, Pei, JF, Lai, LH
core   +1 more source