Results 41 to 50 of about 51,212 (298)

BCR::ABL1‐Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B‐ALL Cells to Enhancer‐Targeting Drugs

Advanced Science, EarlyView.
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng, Trudy Lee Glaser, Jintao Zhu, Mark E. Robinson, Kadriye N. Cosgun, Valeriya Malysheva, Ozgen Deniz, Nicholas T. Crump, Kaiyue Helian, Andrew J. Innes, Richard Burt, Li Sun, George John, Haibin Zhou, Atsunori Kaneshige, Longchuan Bai, Shaomeng Wang, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn   +19 more
wiley   +1 more source

Results of long-term biological monitoring of pacific salmons in the hatcheries of Kamchatsky Krai

Известия ТИНРО, 2015
The following biological problems of the pacific salmons cultivation in Kamchatka are considered on the base of long-term monitoring data (2001-2013): 1) dynamics of cultivated salmons abundance in the water bodies of salmon hatcheries; 2) salmon otolith
Alexander V. Bugaev, Nadezhda A. Rastyagaeva, Natalya N. Romadenkova, Marina A. Kudzina, Denis A. Davidyuk, Tatyana V. Gavruseva, Elena A. Ustimenko, Elena V. Bochkova, Evgeny G. Pogodaev   +8 more
doaj   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Results of monitoring on state of stocks and fisheries of pacific salmon and char of genus Salvelinus in the Magadan Region in 2024

Известия ТИНРО
Results of the salmon fishery in the main fishing areas of the Magadan Region in 2024 are summarized. Data on the forecasted and actual abundance and catch of pacific salmon and char and on the salmon escapement to the spawning grounds are presented. The
L. L. Khovanskaya, I. S. Golovanov, A. M. Korshukova   +2 more
doaj   +1 more source

Pacific salmon of Russian origin: what catches can we count on?

Известия ТИНРО, 2023
Some parameters of the abundance dynamics for the pacific salmon of Russian origin are specified and volume of their possible catch are substantiated for the next decade. The average annual catch for 1907–2022 is amounted as 250 thousand tons.
A. N. Makoedov, A. A. Makoedov
doaj   +1 more source

Salmon and freshwater fisheries in the Solway Firth. Report of the Working Party of North West Water Authority and the Annan District Salmon Fishery Board. [PDF]

, 1986
The Workinq Party of North West Water Authority and the Annan District Salmon Fishery Board's aims were to identify the current problems relating to the salmon and freshwater fisheries in the Solway Firth and its tributaries (embracing the catchments of ...

core  

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Results of pacific salmon fishery in the Sakhalin-Kuril Region in 2024

Известия ТИНРО
Pacific salmon fishery in the Sakhalin-Kuril region in 2024 is considered. Data on the forecasted and actual annual catch are presented, by areas and species.
N. V. Kolpakov, A. A. Makoedov, V. D. Nikitin, O. A. Maznikova, Yu. I. Ignatiev, A. A. Antonov   +5 more
doaj   +1 more source

The pink salmon genome: Uncovering the genomic consequences of a two-year life cycle.

PLoS ONE, 2021
Pink salmon (Oncorhynchus gorbuscha) adults are the smallest of the five Pacific salmon native to the western Pacific Ocean. Pink salmon are also the most abundant of these species and account for a large proportion of the commercial value of the salmon ...
Kris A Christensen, Eric B Rondeau, Dionne Sakhrani, Carlo A Biagi, Hollie Johnson, Jay Joshi, Anne-Marie Flores, Sreeja Leelakumari, Richard Moore, Pawan K Pandoh, Ruth E Withler, Terry D Beacham, Rosalind A Leggatt, Carolyn M Tarpey, Lisa W Seeb, James E Seeb, Steven J M Jones, Robert H Devlin, Ben F Koop   +18 more
doaj   +1 more source

Empirical analyses of the length, weight, and condition of adult Atlantic salmon on return to the Scottish coast between 1963 and 2006 [PDF]

, 2009
Sea age, size, and condition of adult Atlantic salmon (Salmo salar) are prime determinants of individual, and hence population, productivity. To elucidate potential mechanisms, 151 000 records of salmon returning to six Scottish coastal sites over 44 ...
Atlantic Salmon Trust (Funder), Bacon, P.J., EU FinE (Funder), Gurney, W.S.C., MacLean, J.C., Palmer, S.C.F., Smith, G.W., Whyte, B.D.M., Youngson, A.F.   +8 more
core   +1 more source