Results 71 to 80 of about 120,358 (295)

Type III Secretion Effectors with Arginine N-Glycosyltransferase Activity [PDF]

, 2020
Type III secretion systems are used by many Gram-negative bacterial pathogens to inject proteins, known as effectors, into the cytosol of host cells. These virulence factors interfere with a diverse array of host signal transduction pathways and cellular
Araujo Garrido, Juan Luis, Bernal Bayard, Joaquín, Ramos Morales, Francisco   +2 more
core   +1 more source

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

Advanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang, Xiaoxue Ruan, Xudong Hang, Ding Heng, Chang Cai, Liping Zeng, Guoxin Zhang, Lu Zhou, Hongkai Bi, Liang Zhang   +9 more
wiley   +1 more source

Interactions ofSalmonella entericawith dendritic cells [PDF]

Virulence, 2012
Dendritic cells (DCs) form an important link between innate and adaptive immunity. However, DCs are also deployed as vehicles for systemic spread of pathogens. Salmonella is an important gastrointestinal pathogen causing diseases ranging from gastroenteritis to typhoid fever.
Michael Hensel, A. Leoni Swart
openaire   +3 more sources

Loss of very-long O-antigen chains optimizes capsule-mediated immune evasion by Salmonella enterica serovar Typhi. [PDF]

, 2013
UnlabelledExpression of capsular polysaccharides is a variable trait often associated with more-virulent forms of a bacterial species. For example, typhoid fever is caused by the capsulated Salmonella enterica serovar Typhi, while nontyphoidal Salmonella
Bäumler, Andreas J, Crawford, Robert W, Spees, Alanna M, Tsolis, Renée M, Wangdi, Tamding, Xavier, Mariana N   +5 more
core   +1 more source

Disruption of the blood–brain barrier contributes to neurobehavioral changes observed in rheumatic heart disease

Animal Models and Experimental Medicine, EarlyView.
Sydenham's chorea (SC) is the neurological manifestation associated with acute rheumatic fever (ARF), triggered by a group A streptococcal (GAS) infection. Anti‐GAS antibodies cross‐reacting with tissue proteins are implicated in the development of neurological changes. In this study, using an animal model, we demonstrate that a compromised blood–brain
Rukshan Ahamed Mohamed Rafeek, Riya Thapa, Samarjeet Saluja, Bipandeep Banga, David McMillan, Kadaba Sri Sriprakash, Nicholas M. Andronicos, Adam Hamlin, Natkunam Ketheesan   +8 more
wiley   +1 more source

A Carbon Nanotube Immunosensor for Salmonella [PDF]

, 2013
Antibody-functionalized carbon nanotube devices have been suggested for use as bacterial detectors for monitoring of food purity in transit from the farm to the kitchen. Here we report progress towards that goal by demonstrating specific detection of Salmonella in complex nutrient broth solutions using nanotube transistors functionalized with ...
arxiv   +1 more source

Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns [PDF]

, 2017
Three-dimensional models of human intestinal epithelium mimic the differentiated form and function of parental tissues often not exhibited by two-dimensional monolayers and respond to Salmonella in key ways that reflect in vivo infections.
Barrila, Jennifer, Brenneman, Karen, Clemett, Simon J, Crabbé, Aurélie, Crucian, Brian E, Davis, Richard R, Forsyth, Rebecca J, Liu, Yulong, Loscher, Christine, Nelman-Gonzalez, Mayra A, Nickerson, Cheryl A, Nydam, Seth D, Ott, C Mark, Quiriarte, Heather, Roland, Kenneth L, Sams, Clarence, Sarker, Shameema F, Yang, Jiseon   +17 more
core   +1 more source

Citrus Flavonoids as Antimicrobials

Chemistry &Biodiversity, EarlyView.
Citrus flavonoids are powerful and versatile antimicrobials whose mechanism of action often involves disruption of the bacterial membrane, thereby minimizing antimicrobial resistance. This study provides a unified perspective. ABSTRACT Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant ...
Rosaria Ciriminna, Giovanna Li Petri, Giuseppe Angellotti, Rafael Luque, Anne‐Sylvie Fabiano Tixier, Francesco Meneguzzo, Mario Pagliaro   +6 more
wiley   +1 more source

Prevalence of enterobacteriaceae in Tupinambis merianae (Squamata: Teiidae) from a captive facility in Central Brazil, with a profile of antimicrobial drug resistance in Salmonella enterica [PDF]

Phyllomedusa: Journal of Herpetology, 2013
The present study reports the presence of enterobacteriaceae in Tegu Lizards (Tupinambis merianae)from a captive facility in central Brazil. From a total of 30 animals, 10 juveniles and 20 adults (10 males, 10 females), 60 samples were collected, in two ...
Andréa de Moraes Carvalho, Ayrton Klier Péres Júnior, Maria Auxiliadora Andrade, Valéria de Sá Jayme   +3 more
doaj   +2 more sources

Comparison of three diagnostic methods for Salmonella enterica serovars detection in chicken rinse

Pesquisa Veterinária Brasileira
: Salmonella detection is a key point in food safety testing, because of the frequent association of this pathogen with food poisoning in humans. The standard bacteriological tests currently used for Salmonella-detection are time-consuming; therefore ...
Isadora M.O. Corrêa, Larissa Q. Pereira, Isabella G.O. Silva, Rafaela Altarugio, Bruna D. Smaniotto, Tarcísio M. Silva, Adriano S. Okamoto, Raphael L. Andreatti Filho   +7 more
doaj   +1 more source