Results 161 to 170 of about 925,108 (252)

Strategies for enhancing sensitivity in lateral flow assays

open access: yesVIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed   +3 more
wiley   +1 more source

Artificial supplementary food influences hedgehog occupancy and activity patterns more than predator presence or natural food availability

open access: yesWildlife Biology, EarlyView.
Supplementary feeding for declining hedgehog Erinaceus europaeus populations is popular in Great Britain and has been suggested as an important factor in explaining higher densities in urban areas compared with rural ones. Occupancy modelling was used to test whether spatial variation in supplementary feeding, natural food, habitat, or predator ...
Eleanor S. Benjamin   +6 more
wiley   +1 more source

Hunting as anthropogenic sink of biomass or source of carrion? A brief case study based on German hunting bags

open access: yesWildlife Biology, EarlyView.
Dead biomass is a crucial nutrient source for ecosystems. Although hunting residues can subsidize numerous scavenging organisms and are known to drive important zoogeochemical processes at very different scales in the ecosystem, this has received little attention.
Jörg Beckmann   +3 more
wiley   +1 more source

‘The Housewife's Greatest Standby’: Dried Eggs, Gender and Domesticity During the Second World War

open access: yesGender &History, EarlyView.
ABSTRACT This article examines the previously underexplored connections between dried eggs, women and domesticity in Britain during the Second World War. It argues that newsprint and advertisements framed the purchase and use of dried eggs, a novel wartime product, as a means for housewives to contribute to the war effort through domestic labour. Dried
Joel Mead
wiley   +1 more source

Evolutionary and Epidemiological Characterization of Multidrug‐Resistant Escherichia coli Isolated From Pangolins in China

open access: yesIntegrative Zoology, EarlyView.
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang   +8 more
wiley   +1 more source

Microbiome Insights Into Zoonotic Risk at Wildlife–Human Interfaces in a Transitioning Landscape in Thailand

open access: yesIntegrative Zoology, EarlyView.
This study shows how ecological transitions, such as reforestation in Southeast Asia, reshape host–microbe–pathogen dynamics at the wildlife–domestic interface. By integrating long‐read microbiome sequencing, ecological gradients, and statistical and network analysis, we identify host species that disproportionately contribute to pathogen diversity and
Pauline Van Leeuwen   +9 more
wiley   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

open access: yesAllergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan   +16 more
wiley   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander   +5 more
wiley   +1 more source

Trained Immunity in Childhood Vaccination

open access: yesActa Paediatrica, EarlyView.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai   +2 more
wiley   +1 more source

Carriage of antimicrobial‐resistant E. coli in urban stray cats (Felis catus)

open access: yesAustralian Veterinary Journal, EarlyView.
Antimicrobial resistance (AMR) in Escherichia coli is a growing concern in both human and veterinary medicine, driven by the inappropriate use of antimicrobials. Companion animals may act as community reservoirs and sentinels for antimicrobial‐resistant bacteria due to their close contact with humans and other animals.
JS Kuan, S Mukerji, D Hampson, S Abraham
wiley   +1 more source

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