Results 271 to 280 of about 3,413,053 (335)

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Climate change effects in older people's health: A scoping review

Journal of Advanced Nursing, EarlyView.
Abstract Background Climate change has serious consequences for the morbidity and mortality of older adults. Objective To identify the effects of climate change on older people's health. Methods A scoping review was conducted following the Joanna Briggs Institute guidelines and the PRISMA‐ScR checklist.
Eva Mª Montoro‐Ramírez, Laura Parra‐Anguita, Carmen Álvarez‐Nieto, Gema Parra, Isabel Mª López‐Medina   +4 more
wiley   +1 more source

Oral Health and Pneumonia in Adults With Intellectual and Developmental Disabilities: A Scoping Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Introduction Pneumonia is a leading cause of death for people with intellectual and developmental disabilities (IDD), who also have increased risk of oral disease. Given the known relationship between oral disease and pneumonia in similar populations, this review aims to explore what is known about the association between oral health and ...
Katrina Byrne, Dominika Lisiecka, Gary Moran, Blánaid Daly, Isabel Fleischmann, Philip McCallion, Mary McCarron, Caoimhin Mac Giolla Phadraig   +7 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Selection for Tameness in Red Junglefowl Recapitulates Genetic Loci Associated With Domestication‐Related Brain Composition

Molecular Ecology, EarlyView.
ABSTRACT Domestication involves huge phenotypic shifts via strong directional selection. The resulting changes, often termed the Domestication Syndrome, typically encompass numerous traits; however, the most universal of these are changes in reduced fear of humans (tameness) and brain composition.
Carlos Guerrero‐Bosagna, Fábio Pértille, Zahra Moradinour, Rebecca Katajama, Maria Luisa Martin Cerezo, Rie Henriksen, Per Jensen, Dominic Wright   +7 more
wiley   +1 more source

Sex‐Dependent Influence of Major Histocompatibility Complex Diversity on Fitness in a Social Mammal

Molecular Ecology, EarlyView.
ABSTRACT Parasite infections affect males and females differently across a wide range of species, often due to differences in immune responses. Generally, females tend to have stronger immune defences and lower parasite loads than males. The major histocompatibility complex (MHC) plays a crucial role in the adaptive immune response, and extensive ...
Nadine Schubert, Hazel J. Nichols, Francis Mwanguhya, Robert Businge, Solomon Kyambulima, Kenneth Mwesige, Joseph I. Hoffman, Michael A. Cant, Jamie C. Winternitz   +8 more
wiley   +1 more source

Role of the Multicopper Oxidase CueO in Copper Homeostasis Under Anaerobic Conditions in Enterobacteria

Molecular Microbiology, EarlyView.
The periplasmic multicopper oxidase CueO oxidizes cuprous ions (Cu+) to cupric ions (Cu2+), a well‐known process typically coupled with oxygen reduction. In this study, we report unexpected anaerobic phenotypes associated with CueO, suggesting that it may use an alternative electron acceptor in the absence of oxygen.
Jérôme Becam, Maxence Dessertine, Alexandra Vergnes, Laurent Aussel, Benjamin Ezraty   +4 more
wiley   +1 more source

Arthropod ectoparasites of synanthropic rodents in northern‐central Italy

Medical and Veterinary Entomology, EarlyView.
The presence of ectoparasites in synanthropic rodents in various Italian provinces was investigated. Eighty‐one Rattus norvegicus, 49 Rattus rattus and 10 Mus musculus were examined Polyplax spinulosa lice, Myobiidae mites, Laelaps echidninus and Notoedres muris were mainly recovered.
Filippo Maria Dini, Silvia Crucitti, Talita Bordoni, Roberta Galuppi   +3 more
wiley   +1 more source

Diet in Pregnancy: A Review of Current Challenges and Recommendations. A British Nutrition Foundation Briefing Paper

Nutrition Bulletin, EarlyView.
ABSTRACT Pregnancy is a crucial period during which maternal nutrition, weight and lifestyle behaviours have a direct impact on both maternal and fetal health. This briefing paper describes dietary and lifestyle recommendations for women during the preconceptional period and throughout pregnancy, identifying specific factors that can be modified to ...
Kathryn H. Hart, Alyson J. Hill, Javier T. Gonzalez, Anne de la Hunty, Alison M. Gallagher, Sara A. Stanner   +5 more
wiley   +1 more source