Results 31 to 40 of about 169,952 (264)

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

A Case of Postpartum Psychosis Associated with Typhoid and Urinary Tract Infection: A Complex Clinical Presentation [PDF]

Journal of Clinical and Diagnostic Research
Postpartum psychosis (PPP) is a rare but severe psychiatric disorder occurring shortly after childbirth. The present report describes a 37-year-old female who, three weeks after an uncomplicated vaginal delivery, developed acute psychosis coinciding with
Althea Sukhato Wotsa , Tatonginla Jamir
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Quantitative Risk Assessment Model of Human Salmonellosis Resulting from Consumption of Broiler Chicken

Diseases, 2019
(1) Background: Salmonella infections are a major cause of illnesses in the United States. Each year around 450 people die from the disease and more than 23,000 people are hospitalized.
Luma Akil, H. Anwar Ahmad
doaj   +1 more source

Clinical and microbiological characterization of Salmonella spp. isolates from patients treated in a university hospital in South America between 2012–2021: a cohort study

BMC Infectious Diseases, 2023
Background Salmonellosis is a major cause of morbidity and mortality and one of the most frequent etiologies of diarrhea in the world. Mortality due to Salmonellosis in Latin America still poorly understood, and there is a lack of studies that evaluate ...
Fernando Rosso, David E. Rebellón-Sánchez, Julio Llanos-Torres, Leidy Johanna Hurtado-Bermudez, Laura Ayerbe, John Harold Suárez, Nicolás Orozco-Echeverri, Cristhian Camilo Rojas-Perdomo, Isabel Lucia Zapata-Vasquez, Jaime Patiño-Niño, Luis Gabriel Parra-Lara   +10 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Mechanisms for the Invasion and Dissemination of Salmonella

Canadian Journal of Infectious Diseases and Medical Microbiology, 2022
Salmonella enterica is a gastroenteric Gram-negative bacterium that can infect both humans and animals and causes millions of illnesses per year around the world.
Qiao Li
doaj   +1 more source

Patterns of multiple enteric infections in a 10-year longitudinal study in British Columbia, Canada

International Journal of Infectious Diseases, 2022
Purpose: Enteric infections are a global public health issue, in part because long-term sequelae can occur post-infection. Complicating risk estimation of sequela, such as acute kidney injury and inflammatory bowel diseases, after infections is the fact ...
M. Gohari, M. Taylor, M. Mackinnon, D. Panagiotoglou, E. Galanis, S. Majowicz   +5 more
doaj   +1 more source