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Quinolones in Salmonella typhi Infection [PDF]

open access: possibleDrugs, 1993
The quinolones possess a high degree of in vitro activity against enteric bacteria, including Salmonella. This observation, coupled with the limitations of current antityphoid agents, has resulted in the evaluation of quinolones in the therapy of S. typhi infection, including both enteric fever and chronic intestinal carriage.
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Salmonella typhi Meningitis in a Neonate

Archives of Pediatrics & Adolescent Medicine, 1977
Salmonella is a relatively rare, but noteworthy cause of purulent meningitis in infancy. At one time, the prognosis for infants with salmonella meningitis was thought to be uniformly poor, 1,2 but recently a number of cases involving successfully treated patients have been reported. 3-6 We are reporting a case of Salmonella typhi meningitis in a 3-week-
Barbara K. Burton   +3 more
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Recurrent Salmonella typhi Peritonitis

JAMA: The Journal of the American Medical Association, 1980
SALMONELLA typhi peritonitis is rarely seen in the United States today. 1 Recently the incidence of typhoid in the United States has been 0.2 cases per 100,000 people per year, with one third of the cases attributed to foreign travel. 2 In older series 2% of patients with typhoid had perforation of viscera and peritonitis. At the Kings County Hospital
Dennis Cleri   +2 more
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Salmonella Typhi Murium in Penguins

Journal of Comparative Pathology and Therapeutics, 1947
Summary An outbreak of apparently infectious disease among penguins is described. Salmonella typhi murium was isolated from some of the penguins. Two penguins were found to be healthy carriers of the organism. The carriers were successfully treated by large doses of “sulpha” drugs. Penguins can tolerate up to 1 g.
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A novel lineage of ceftriaxone-resistant Salmonella Typhi from India that is closely related to XDR S. Typhi found in Pakistan.

Clinical Infectious Diseases, 2019
Two MDR Salmonella Typhi isolates from India were found by whole genome sequencing to be closely related to the 2016 XDR S. Typhi outbreak strain from Pakistan. The Indian isolates have no chromosomal AMR cassette, but carry the IncY plasmid p60006. Both
R. Sah   +14 more
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Reevaluating Fluoroquinolone Breakpoints for Salmonella enterica Serotype Typhi and for Non-Typhi Salmonellae

Clinical Infectious Diseases, 2003
Salmonella enterica infections cause considerable morbidity and mortality worldwide. Antimicrobial therapy may be life-saving for patients with extraintestinal infections with S. enterica serotype Typhi or non-Typhi salmonellae. Because antimicrobial resistance to several classes of traditional first-line drugs has emerged in the past several decades ...
John A. Crump   +3 more
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Siderophore production by Salmonella typhi

Biochemical and Biophysical Research Communications, 1988
This study was initiated to determine the mechanism of iron-uptake in Salmonella typhi. When stressed for iron, microorganisms produce siderophores to obtain the necessary nutrient. Generally two types of siderophores exist: the phenolate-type predominantly produced by bacteria and the hydroxamate-type commonly secreted by fungi.
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A biotyping Scheme for Salmonella typhi

Kenya Veterinarian, 2009
Thirty-nine isolates of Salmonella typhi (S. typhi) were studied using biotyping and antibiogram typing. Biotyping divided the isolates into six distinct biotypes on the basis of three biochemical tests, which includedfermentation of bitter sugars: xylose and rhamnose; and reaction in Stern’s glycerol.
GI Merekaje, MO Odongo
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THE PRODUCTION AND PROPERTIES OF SALMONELLA TYPHI SPHEROPLASTS

Canadian Journal of Microbiology, 1964
S. typhi spheroplasts were produced by growing typhoid organisms in a liquid semisynthetic medium containing 1.5 to 2.0% glycine. The addition of traces of magnesium and glucose concentrations of 0.5 to 2.0% was required for optimal growth conditions.
L. Greenberg, B. B. Diena, R. Wallace
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Transferable Chloramphenicol Resistance in Salmonella typhi

Nature, 1972
WE report an outbreak of typhoid from which Salmonella typhi strains carrying R factors to multiple antibiotics including Chloramphenicol have been isolated. Transferable drug resistance is common in Salmonella species which cause food poisoning1,2 but not in S.
C. K. J. Paniker, K. N. Vimala
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