Results 51 to 60 of about 64,944 (219)

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Prevalence, Risk Factors, and Human Health Implications of Salmonella enterica and Campylobacter spp. in Vermont Backyard Poultry

Zoonoses and Public Health, Volume 72, Issue 7, Page 654-668, November 2025.
ABSTRACT Introduction Backyard poultry (BYP) are increasingly linked to cases of campylobacteriosis and salmonellosis. Methods Between 2022 and 2024, soiled bedding samples from 70 BYP farms were tested for Campylobacter spp. and/or Salmonella enterica. Results Nine farms (12.86%) had at least one sample positive for S.
Chelsey A. Patch, Katalin M. Larsen, Cheryl M. Armstrong, Siddhartha Kanrar, Alessandra M. Michaelides, Purna Chakraborty, Kelcey Harper, Valarie Devlin, Lorrie Martin, Alia Lunna, Hannah L. Blackwell, Sarah C. Nguyen, Anna Penny, Andrea J. Etter   +13 more
wiley   +1 more source

Sensitivitas Salmonella Sp. Penyebab Demam Tifoid Terhadap Beberapa Antibiotik di Rumah Sakit Immanuel Bandung

Majalah Kedokteran Bandung, 2009
Typhoid fever is an enteric fever caused by Salmonella sp. especially Salmonella typhi and Salmonella paratyphi. Various antibiotics used for therapy beside chloramphenicol as drug of choice.
Yanti Mulyana
doaj   +1 more source

Diagnostic Challenge of Xanthogranulomatous Salpingo‐Oophoritis in an 8‐Year‐Old Girl in a Low Resource‐Setting: A Rare Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Xanthogranulomatous oophoritis is an extremely rare, chronic inflammatory condition of the ovary characterized by the replacement of normal ovarian tissue with lipid‐laden macrophages, plasma cells, and lymphocytes. When the genital tract is involved, this most commonly affects the endometrium, whereas ovarian and fallopian tube involvement is
John Lugata, Kristen Riley, Laetitia Makower, Baraka Shao, Tecla Lyamuya, Alex Mremi   +5 more
wiley   +1 more source

ANTAGONISM TESTING ON AN ETHANOL EXTRACT PREPARATION OF YELLOW ROOT STICKS (Arcangelisia flava L. Merr) TOWARD Yersinia enterocolitica AND Salmonella typhi BACTERIA

Jurnal Pendidikan Matematika dan IPA
Yellow root (Arcangelisia flava L. Merr) contains ethanol compounds which is able to inhibit bacterial growth, both gram negative bacteria such as Stapylococcus aureus, Shigella sp., and Escherichia coli, as well as gram positive bacteria such as ...
Noor Hujjatusnaini, Astuti Muh Amin, Rafif Ibnu Widyadana, Nur Annisa, Nor Mila, Latifah Nur Aín   +5 more
doaj   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang, Qianqian Wang, Jiaming Zhang, Bingyu Li, Yuke Li, Zhengbo Chen, Dandan Guo, Shuying Feng   +7 more
wiley   +1 more source

Antimicrobial Effect of Silver Nanoparticles and Combination with Cotrimoxazole against Salmonella Typhi in Vitro and in Animal Model [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: Salmonella typhi is a large group of gram-negative bacilli with Enterobacteriaceae and common pathogens between humans and animals, which is the main cause of typhoid fever in humans.
Mina Javadi, Hossein Soltani, Rasoul Shokri   +2 more
doaj  

Current status and future perspectives of multi‐modal bacteria‐based cancer therapies

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan, Siyu Zhu, Wenyu Wang, Yuetong Liu, Yutong Zhou, Hao Li, Bofeng Liu, Qin Xia, Lili Huang, Lei Dong   +9 more
wiley   +1 more source

Extensively Drug-Resistant Typhoid: Antibiotic Susceptibility Pattern of an Emerging Menace in Karachi

Pakistan Journal of Medicine and Dentistry
Background: Salmonella typhi, a rod-shaped Gram-negative bacterium that stands responsible for causing typhoid fever, in places with poor sanitation and polluted water.
Syed Mehmood Hasan, Sadaf Razzak, Asma Shabbir, Syed Muhammad Hasan, Masood Husain   +4 more
doaj   +1 more source

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

Exploration, Volume 5, Issue 5, October 2025.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye, Wenhua Huang, Shujuan Yu, Yan Guo, Peng Sun, Ziyuan Chen, Linhui Hao, Yan Zhang, Caixia Li, Yongqiang Jiang, Jun Wu, Li Zhu, Hengliang Wang, Chao Pan   +13 more
wiley   +1 more source