Results 71 to 80 of about 64,944 (219)

The Role of Carbenicillin as an Inhibitor of the Biofilm Regulator CsgD in Salmonella Typhimurium

open access: yesMicrobiologyOpen, Volume 14, Issue 5, October 2025.
Salmonella Typhimurium biofilms, driven by the CsgD protein, enhance antibiotic resistance and pose public health concerns. This study employed molecular docking to screen 145 FDA‐approved antibiotics, identifying carbenicillin as a potent CsgD inhibitor. Molecular dynamics simulations confirmed stable carbenicillin‐CsgD binding.
Negar Narimisa   +3 more
wiley   +1 more source

Old tools, new applications: Use of environmental bacteriophages for typhoid surveillance and evaluating vaccine impact.

open access: yesPLoS Neglected Tropical Diseases
Typhoid-conjugate vaccines (TCVs) provide an opportunity to reduce the burden of typhoid fever, caused by Salmonella Typhi, in endemic areas. As policymakers design vaccination strategies, accurate and high-resolution data on disease burden is crucial ...
Yogesh Hooda   +10 more
doaj   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin   +15 more
wiley   +1 more source

ISOLASI DAN KARAKTERISASI BAKTERIOFAG SPESIFIK SALMONELLA TYPHI DARI KULIT AYAM

open access: yesJurnal Teknologi Pertanian, 2018
Salmonella enterica serovar Typhi merupakan bakteri gram negatif yang menyebabkan demam tifoid sangat endemik di Indonesia. Penggunaan antibiotik yang tidak terkontrol menimbulkan kasus resistensi yang menyebabkan tidak efektifnya pengobatan.
Sri Hardanti   +2 more
doaj   +1 more source

Evaluation of the Antioxidant, Anticancer, and Antibacterial Activities of Flower and Leaf Extracts of Chrysanthemum indicum

open access: yesChemistryOpen, Volume 14, Issue 10, October 2025.
The tested methanolic extract of Chrysanthemum indicum flower and leaf is a rich source of bioactive molecules with significant antioxidant activity at low doses, potential anticancer effects at lower concentrations, and antimicrobial activities against Gram‐positive and Gram‐negative species, which is consistent with the plant's traditional ...
Tarad Abalkhail   +6 more
wiley   +1 more source

Presence of Enteric Fever with Unusual Clinical Scenarios: A Case Series [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Salmonella species are associated with bacteraemia, diarrhoea, as well as focal infections. Salmonella Typhi is the most pathogenic species. Salmonella Paratyphi B commonly affects immunocompromised hosts.
Vrushali Thakar   +4 more
doaj   +1 more source

Phylogenetic relationship of Gram Negative Bacteria of Enterobacteriaceae Family in the Positive Widal Blood Cultures based on 16S rRNA Gene Sequences

open access: yesIndonesian Journal of Biotechnology, 2015
The purpose of this study was to analyze the phylogenetic relationship of Gram negative bacteria (3strains of Salmonella typhi, 1 strain of Escherichia coli, 1 strain of Serratia marcescens, and 3 strains of Enterobactercloacae) of Enterobacteriaceae ...
Sri Darmawati   +4 more
doaj  

Trends of antibiotic susceptibility of Salmonella Enterica serovar typhi and paratyphi in an urban hospital of Dhaka city over 6 years period

open access: yesIMC Journal of Medical Science, 2011
The antibiotic resistance pattern of salmonella is ever changing over time. The present study is a retrospective analysis of rate of isolation of Salmonella Typhi and Paratyphi and their antibiotic resistance pattern over 6 years period in an urban ...
Khandaker Shadia   +7 more
doaj  

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