Results 111 to 120 of about 383,285 (360)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Resistance of Salmonella typhimurium to Tetracyclines

Experimental Biology and Medicine, 1958
SummaryCultures of Salmonella typhimurium isolated from man and animals prior to 1948 and cultures of the same serotype isolated from man and fowls after Jan. 1956 were compared for resistance to several antibiotic substances. Significant results were obtained only with tetracyclines.
Carolyn R. Huey, P. R. Edwards
openaire   +3 more sources

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, EarlyView.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Stress induced Salmonella Typhimurium recrudescence in pigs coincides with cortisol induced increased intracellular proliferation in macrophages

Veterinary Research, 2011
Salmonella Typhimurium infections in pigs often result in the development of carriers that intermittently excrete Salmonella in very low numbers. During periods of stress, for example transport to the slaughterhouse, recrudescence of Salmonella may occur,
Verbrugghe Elin, Boyen Filip, Van Parys Alexander, Van Deun Kim, Croubels Siska, Thompson Arthur, Shearer Neil, Leyman Bregje, Haesebrouck Freddy, Pasmans Frank   +9 more
doaj   +1 more source

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

PLoS Pathogens, 2015
Salmonella enterica serovar Typhimurium is arguably the world’s best-understood bacterial pathogen. However, crucial details about the genetic programs used by the bacterium to survive and replicate in macrophages have remained obscure because of the ...
S. Srikumar, Carsten Kröger, Magali Hébrard, A. Colgan, S. Owen, Sathesh K. Sivasankaran, Andrew D. S. Cameron, K. Hokamp, J. Hinton   +8 more
semanticscholar   +1 more source

Salmonella Typhimurium and Multidirectional Communication in the Gut [PDF]

Frontiers in Microbiology, 2016
The mammalian digestive tract is home to trillions of microbes, including bacteria, archaea, protozoa, fungi, and viruses. In monogastric mammals the stomach and small intestine harbor diverse bacterial populations but are typically less populated than the colon.
Thomas H. Welsh, Robert C. Alaniz, Ronald D. Randel, Elena V. Gart, Sara D. Lawhon, Jan S. Suchodolski   +5 more
openaire   +4 more sources

Loss of very-long O-antigen chains optimizes capsule-mediated immune evasion by Salmonella enterica serovar Typhi. [PDF]

, 2013
UnlabelledExpression of capsular polysaccharides is a variable trait often associated with more-virulent forms of a bacterial species. For example, typhoid fever is caused by the capsulated Salmonella enterica serovar Typhi, while nontyphoidal Salmonella
Bäumler, Andreas J, Crawford, Robert W, Spees, Alanna M, Tsolis, Renée M, Wangdi, Tamding, Xavier, Mariana N   +5 more
core   +1 more source

Recent Advances and Constructing Strategies of Chemiluminescence‐ and Bioluminescence‐Based Photodynamic Therapy

ChemPhotoChem, EarlyView.
Photodynamic therapy (PDT) is a noninvasive therapy for cancer and many other diseases. A PDT system includes three key components: a light source, photosensitizers (PSs), and oxygen. Internal light sources, such as chemiluminescence (CL) and bioluminescence (BL), trigger PDT without external irradiation, allowing for more flexibility.
Yuqin Ge, Shuyan Xue, Zhonghua Chen
wiley   +1 more source

Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

PLoS Neglected Tropical Diseases, 2015
Two lineages of Salmonella enterica serovar Typhimurium (S. Typhimurium) of multi-locus sequence type ST313 have been linked with the emergence of invasive Salmonella disease across sub-Saharan Africa.
Chinyere K. Okoro, Lars Barquist, T. Connor, S. Harris, S. Clare, M. Stevens, M. Arends, C. Hale, Leanne Kane, D. Pickard, J. Hill, K. Harcourt, J. Parkhill, G. Dougan, R. Kingsley   +14 more
semanticscholar   +1 more source

SELFER MUTANTS OF SALMONELLA TYPHIMURIUM [PDF]

Genetics, 1963
The name selfer has been given to a mutant strain of bacteria in which transduction with homologous phage gives rise to a significantly larger number of wild-type variants than occurs by spontaneous reversion in uninfected control bacteria. Experiments with 201 auxotrophic mutants of Salmonella typhimurium representing 22 gene loci carried in 12 ...
openaire   +3 more sources