Results 31 to 40 of about 3,116,577 (307)

American Grand Strategy in the Mediterranean during World War II (Book Review) by Andrew Buchanan [PDF]

open access: yes, 2018
Review of American Grand Strategy in the Mediterranean during World War II by Andrew ...
Salt, Alexander
core   +1 more source

The food safety impact of salt and sodium reduction initiatives [PDF]

open access: yes, 2014
Excessive or high salt or sodium intake is known to cause hypertension and other diseases. Within the United Kingdom voluntary targets for salt reduction have been set and laid out in the Secretary of State responsibility deal.
ACMSF   +6 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Clinical and psychological characteristics of patients with arterial hypertension, consuming an increased amount of salt

open access: yesАрхивъ внутренней медицины, 2015
Objective: to Study the potential development of links between the formation of neurotic disorders personality and high salt intake (S) with food in patients with arterial hypertension (AH).Materials and methods: the study involved 229 patients with ...
O. B. Poselyugina
doaj   +1 more source

A cost effectiveness analysis of salt reduction policies to reduce coronary heart disease in four Eastern Mediterranean countries. [PDF]

open access: yes, 2014
BACKGROUND: Coronary Heart Disease (CHD) is rising in middle income countries. Population based strategies to reduce specific CHD risk factors have an important role to play in reducing overall CHD mortality.
Abou Mayaleh, M.   +57 more
core   +7 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Clinical and functional manifestations of hypervolemia in patients with arterial hypertension

open access: yesКардиоваскулярная терапия и профилактика, 2011
Aim. To identify clinical and functional manifestations of hypervolemia in patients with arterial hypertension (AH). Material and methods. In total, 440 patients with Stage I-II AH were examined, including assessment of salt taste sensitivity threshold ...
O. B. Poselyugina   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Stochastic modeling of soil salinity [PDF]

open access: yes, 2010
A minimalist stochastic model of primary soil salinity is proposed, in which the rate of soil salinization is determined by the balance between dry and wet salt deposition and the intermittent leaching events caused by rainfall events.
Daly, E.   +4 more
core   +2 more sources

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