Results 61 to 70 of about 310,116 (269)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Research results of the screw dispenser of dry bulk feed components

open access: yesАграрная наука Евро-Северо-Востока
In the production of compound feeds, it is necessary to follow the recipe at the time of introducing all the necessary components, for which various types of dispensers are used.
S. Yu. Bulatov, A. N. Pronin
doaj   +1 more source

Modification of aluminium alloys with rare metals – the basis for advanced materials in construction and transport

open access: yesНанотехнологии в строительстве, 2016
The method of process powder injection into aluminum melt shows much promise. Scandium is injected by the high-temperature exchange reaction between the salt melt and aluminum. The best salt compositions were selected.
Skachkov Vladimir Mikchaylovich   +1 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Optimal artificial urine formulations for in vitro urolithiasis models

open access: yesFrontiers in Urology
PurposeTo develop and characterize standardized in vitro artificial urine (AU) models for three major stone-forming environments—calcium oxalate (CaOx), uric acid (UA), and infection-related struvite—and to identify assay operating conditions that ...
Deok Hyun Han, Jae Hoon Chung
doaj   +1 more source

The polyphasic evolution of a saline soil

open access: yesLucrările Seminarului Geografic "Dimitrie Cantemir", 2018
The paper emphasizes the polyphasic evolution of a saline soil and its development towards a zonal soil. Most saline soils have formed in river beds, on parental materials made up of stratified fluvial deposits.
Daniela Răducu   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Salt marshes [PDF]

open access: yesCurrent Biology, 2014
Salt marshes are unique ecosystems that are brimming with diversity, and provide crucial shelter to coastal communities.
openaire   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

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