Results 71 to 80 of about 310,116 (269)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

With a pinch of salt [PDF]

Sexually Transmitted Infections, 2001
“Rob, I know you're a doctor—can I have a word about your son.” The reception class nursery nurse's words chilled me to the bone, as Jamie (aged 5) had been off colour for a few days. “I am a bit worried about the rash he has got on his face. Three other children in the class have a similar rash—do you think it is infectious?” I looked at the bright ...
openaire   +2 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Crystal structures of three salts of the triphenylsulfonium ion

Acta Crystallographica Section E: Crystallographic Communications
The reactions of triphenylsulfonium chloride ([TPS][Cl]) with various acids in methanol yield the corresponding salts triphenylsulfonium triiodide, C18H15S+·I3− or [TPS][I3] (I), triphenylsulfonium perchlorate, C18H15S+·ClO4− or [TPS][ClO4] (II), and ...
Rylan Artis, Waylan Callaway, Elizabeth Heyward, Naomi Reyes, Gavin Roberts, Kaitlyn Van Ostenbridge, Clifford W. Padgett, Will E. Lynch   +7 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Influence of Tetrabromobisphenol-A on the Fate and Behavior of Zinc Oxide Nanoparticles Affected by Salts, Humic Acid, and Bovine Serum Albumin in Water Systems

Toxics
The environmental release of zinc oxide nanoparticles (ZnO-NPs) may have consequences for ecosystems. The behavior and environmental effects of ZnO-NPs could change due to their interactions with other existing substances.
Anwar Ul Haq Khan, Yanju Liu, Ravi Naidu, Cheng Fang, Ho Kyong Shon   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Deliquescence‐induced wetting and RSL‐like darkening of a Mars analogue soil containing various perchlorate and chloride salts

Geophysical Research Letters, 2016
Recurring slope lineae (RSL) are flow‐like features on Mars characterized by a local darkening of the soil thought to be generated by the formation and flow of liquid brines.
Jacob Heinz, Dirk Schulze‐Makuch, Samuel P. Kounaves   +2 more
doaj   +1 more source