Results 31 to 40 of about 1,385,141 (252)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
La salud mental en primera persona. Los comités de personas expertas
Revista Española de Discapacidad, 2016 Salud Mental España (2016): “La salud mental en primera persona. Los comités de personas expertas”, Revista Española de Discapacidad, 4 (1): 241-247.
Salud Mental España
doaj
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Medicina, 1985 <p>Accident: Analysis and Prevention. New York. Bimestral <br />Acodal. Bogotá. Irregular <br />Acta Chirurgica Scandinavica. Estocolmo. 8 números al año <br />Acta Psiquiátrica y Psicológica de América Latina.
Ministerio de Salud
doaj
, 2005 El nuevo reto de quienes trabajan en salud es la prevención de enfermedades a través de una cultura de promoción de la salud, rubro que en los próximos 70 años orientará las políticas del Ministerio de Salud (MINSA), tal como lo dijo la titular de salud,
Instituto Nacional de Salud
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Medicina, 1985 <p>¿<strong>QUE ES? </strong></p><p>La gran cantidad de información bibliográfica aparecida en revistas, boletines, diarios, etc. imposibilita al especialista y profesional permanecer actualizado en su área.
Ministerio de Salud
doaj
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source