Results 41 to 50 of about 2,451,032 (303)

Salud oral en adolescentes: Escuelas saludables

open access: yesRevista Científica de Salud UNITEPC, 2022
Introducción: El Índice de CPO-D es uno de los indicadores epidemiológicos más comunes empleado para evaluar la prevalencia de dientes cariados, perdidos y obturados, se define en dentición permanente a partir de los 12 años y según parámetros establecidos es interpretado la severidad; el objetivo es determinar el Índice de CPO-D en los adolescentes de
Teresa Paola Canchari Pereyra   +5 more
openaire   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Epistemological bases of the debate on linguistic sexism. [PDF]

open access: yes, 2016
En este trabajo analizamos los supuestos epistemológicos que subyacen a las diferentes posturas en torno del tema del sexismo lingüístico: la dicotomía lengua / habla; la independencia vs.
Márquez Guerrero, María Salud
core  

Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]

open access: yes, 2014
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora   +7 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Bacteremia caused by an Acinetobacter junii strain harboring class 1 integron and diverse DNA mobile elements [PDF]

open access: yes, 2014
INTRODUCTION: Infections caused by Acinetobacter junii are rarely reported. However, some outbreaks of septicemia in neonates and pediatric oncology patients, as well as meningitis, peritonitis, and ocular infection have been described.
Almuzara, Marisa   +7 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Virulence profile comparison between LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle and humans [PDF]

open access: yes, 2010
For comparison purposes, the prevalence of 8 virulence markers was investigated, by PCR, in 153 cattle and 47 human Locus for Enterocyte Effacement (LEE)-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated in Argentina.
Galli, Lucía   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

La salud mental en primera persona. Los comités de personas expertas

open access: yesRevista Española de Discapacidad, 2016
Salud Mental España (2016): “La salud mental en primera persona. Los comités de personas expertas”, Revista Española de Discapacidad, 4 (1): 241-247.
Salud Mental España
doaj  

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