Results 61 to 70 of about 2,451,032 (303)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Understanding the twist-bend nematic phase: the characterisation of 1-(4-cyanobiphenyl-4'-yloxy)-6-(4-cyanobiphenyl-4'--yl)hexane (CB6OCB) and comparison with CB7CB [PDF]
, 2016 The synthesis and characterisation of the nonsymmetric liquid crystal dimer, 1-(4-cyanobiphenyl-40-yloxy)-6- (4-cyanobiphenyl-40-yl)hexane (CB6OCB) is reported.
Díez Berart, Sergio +6 more
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Informe de Bellagio sobre agricultura saludable, nutrición saludable, población saludable
Nutrición Hospitalaria, 2013 El informe del Bellagio sobre agricultura saludable, nutrición saludable, población saludable es el resultado de la reunión mantenida en el Centro Bellagio de la Fundación Rockefeller en el Lago de Como en Italia, entre el 29 de octubre y el 2 de noviembre de 2012. La reunión basada en la ciencia, fue orientada hacia la política.
Simopoulos, Artemis P +2 more
openaire +4 more sources
¿Salud individual y salud colectiva?
Anales de la Facultad de Medicina, 2018 A través de la historia el concepto de salud ha ido variando, así como las definiciones de la salud pública, salud individual y salud colectiva, incluyendo a la salud como un derecho fundamental de los ciudadanos. En este número, Anales de la Facultad, abarca diversos temas relacionados a lo que serían problemas de salud colectiva y salud individual ...
openaire +5 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Importancia en el sistema de salud de la infección por Treponema pallidum, la enfermedad de Chagas y el virus de la inmunodeficiencia humana 1 en amerindios de Argentina: un estudio observacional [PDF]
, 2017 El objetivo de este trabajo fue estimar la prevalencia de Treponema pallidum, Trypanosoma cruzi y virus de la inmunodeficiencia humana (HIV-1) en 5 comunidades originarias de Argentina.
Berini, Carolina Andrea +10 more
core +2 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
A Photovoice Evaluation of Coping Mechanisms Among Children of Immigrants [PDF]
, 2018 In this community based participatory research, photovoice was used to shine a light on the coping mechanisms of children of immigrants. Photovoice was chosen to give the children a platform to explore and identify how they cope with difficult ...
Garzon-Florez, MPHc, Paula +2 more
core +1 more source