Results 121 to 130 of about 1,751,732 (246)

UV signature mutation hyperhotspots as genomic dosimeters

open access: yesPhotochemistry and Photobiology, EarlyView.
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon   +12 more
wiley   +1 more source

La investigación como instrumento innovador de la sanidad ambiental [PDF]

open access: yes, 2011
La difusión de resultados de investigaciones muestran que el medio ambiente es un factor que contribuye a la aparición de enfermedades de diversos orígenes y que las situaciones de riesgo son inherentes a los procesos de producción y surgen en distintas ...
Cassanha Galvão, Luiz Augusto   +5 more
core  

Intermittent hand and forearm immersion in 20°C water attenuates thermal, cardiovascular, and perceptual strain in older adults during heat stress

open access: yesExperimental Physiology, EarlyView.
Abstract Adults >65 years of age experience deleterious health effects during extreme heat events at a greater rate than any other age cohort. The purpose of this study was to identify the effectiveness of acute intermittent hand and forearm (H+F) water immersion and/or chronic (7 week) folic acid supplementation on reducing thermal and cardiovascular ...
Rachel M. Cottle   +5 more
wiley   +1 more source

Estratégias transfronteiriças, transdisciplinares e interculturais para a sustentação da saúde humana e ambiental na Amazónia [PDF]

open access: yes
Climate and non-climate factors threaten the health of the population and the socio-ecological systems of the Amazon. Since the pressures resulting from deforestation, resource extraction, crime and land grabbing in the region transcend geopolitical ...
Bustos Echeverry, Daniel   +5 more
core  

Macro‐ and microcirculatory factors affecting foot temperature change during walking

open access: yesExperimental Physiology, EarlyView.
Abstract Change in skin temperature is a complex process affected by several factors. During walking, increased microcirculatory activity, such as muscle metabolism, could increase foot temperature. The ensuing macrocirculatory responses, such as increased leg blood flow (LBF), might also increase foot temperature.
Jose G. Anguiano‐Hernandez   +5 more
wiley   +1 more source

Evolución del marco normativo de la salud ambiental en colombia [PDF]

open access: yes, 2013
Este ensayo presenta un análisis sobre la evolución del manejo de la salud ambiental en el país desde el Código Sanitario nacional (1979) hasta la ley 100 y Ley 99 de 1993 y la Política de Salud Ambiental de Bogotá D.C.
Garcia-Ubaque, Cesar Augusto   +2 more
core  

Reflexiones acerca de la relación ambiente y salud. Pensando en ambientes saludables

open access: yes, 2016
La salud ambiental supone en la actualidad una preocupación global debido a que comprende aquellos aspectos de la salud humana, incluida la calidad de vida y el bienestar social, que son determinados por factores ambientales físicos, químicos, biológicos, sociales y psico-sociales, como así lo define la Organización Mundial de la Salud.
Hernández Flórez, Luis Jorge   +7 more
openaire   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor   +5 more
wiley   +1 more source

Video Intro eje 2: Salud Ambiental I

open access: yes, 2018
Este es un video relacionado con salud ambiental, realizado por el mismo autor en el estudio de grabación institucional o fuera de este. Presenta aspectos teórico prácticos del contenido en los que se desea precisar, profundizar o puntualizar. Permite la
Erazo, Jenny
core  

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