Results 141 to 150 of about 1,751,732 (246)

Quantitation of Cirtuvivint (SM08502) in Human Plasma by LC–MS/MS

Biomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT CDC‐like kinases (CLK) and dual‐specificity tyrosine‐regulated kinases (DYRK) are protein kinases involved in various cellular functions, mRNA splicing, and DNA damage repair. CLK/DYRK kinases have been implicated in many disorders such as diabetes, neurodegenerative diseases, and cancer.
Julianne L. Holleran, Joshua J. Deppas, Ye Feng, Michael J. Hochman, Evan C. Chen, Maximilian Stahl, Steven D. Gore, Timothy W. Synold, Jan H. Beumer, Raman Venkataramanan, Robert A. Parise   +10 more
wiley   +1 more source

Environmental health during extreme heat: challenges for the practice of safe physical activity in childhood and adolescence. [PDF]

Cad Saude Publica
Freitas F, Fogagnolo C, Dornfeld RL, Vitolo MR, Antônio MÂ, Brandão MÂB.   +5 more
europepmc   +1 more source

Ambiente saludable

, 2021
Comité de la Subcuenca del Río Jucuapa, Matagalpa (Nicaragua), CATIE, Managua (Nicaragua), Agencia Sueca para el Desarrollo Internacional, Managua (Nicaragua).   +2 more
openaire   +1 more source

Resolution and Quantitation of Ribonucleosides and Deoxyribonucleosides in Digested Genomic DNA by UHPLC–MS/MS

Biomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT Deoxyuridine (dUrd) is often misincorporated into genomic DNA in cancer patients receiving antimetabolite chemotherapy. This activates base excision repair and recruits ataxia telangiectasia‐mutated and Rad3‐related (ATR), which coordinates DNA repair with nucleotide metabolism by facilitating ribonucleotide reductase (RNR) activity ...
Joshua J. Deppas, Reyna Jones, Robert A. Parise, Pinakin Pandya, Christopher J. Bakkenist, Jan H. Beumer   +5 more
wiley   +1 more source

Active Electromagnetic Interference Suppression for MRI and Proton Resonance Frequency Shift Thermometry During MRI‐Guided Microwave Ablation

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1572-1588, October 2026.
ABSTRACT Purpose To develop a software‐based active electromagnetic interference (EMI) suppression (AES) framework on whole‐body multi‐channel MRI systems for reliable MRI and MR thermometry during MRI‐guided microwave ablation (MWA). Methods In addition to primary imaging coils, an unloaded standard body array coil was positioned outside the imaging ...
Qing Dai, Jason Chiang, Shu‐Fu Shih, Wenqi Zhou, David S. K. Lu, Holden H. Wu   +5 more
wiley   +1 more source

Arc‐ZTE: Continuously‐Slewed Zero‐TE Imaging With Incoherent Temporal Sampling for Near‐Silent Dynamic MRI

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1726-1740, October 2026.
ABSTRACT Purpose To enable flexible dynamic and DCE MRI with low acoustic noise and high spatiotemporal resolution using zero echo time (ZTE) imaging. Methods This work proposes Arc‐ZTE, a technique in which the readout gradients of ZTE are continuously‐slewed to form arcs in k‐space that are sequentially rotated to yield an incoherent trajectory ...
Shreya Ramachandran, Tobias C. Wood, Gavin Zhang, Ali B. Syed, Shreyas S. Vasanawala, Michael Lustig   +5 more
wiley   +1 more source

Valuing reductions in the risk of death in benefit-cost analyses of environment- and climate-health actions. [PDF]

Bull World Health Organ
Pega F, Momen NC, Agyemang SA, Bojke L, Costa-Font J, de Preux L, Fenichel EP, Gordon B, Hensher MC, Johnston R, Krishnamoorthy Y, Kolimenakis A, Malik MA, Matsuura H, Nghiem N, O'Hare B, Rathi M, Robinson LA, Campbell-Lendrum D.   +18 more
europepmc   +1 more source

Comunicação Oral apresentado no XII Congresso Espanhol em Saúde Ambiental

, 2013
No disponible.Not available.Não ...
Revista de Salud Ambiental, Editor
core  

Strategy for modular assembly of tetravalent, multispecific antibodies

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Multispecific, multivalent antibodies (Abs) are a burgeoning class of drugs that dramatically expand the pharmacological repertoire beyond traditional therapeutic Abs. Here, we present a simple, modular approach to developing multispecific, multivalent Abs based on a Fab‐phage library with a single light chain.
Evan Mallette, Levi L. Blazer, Craig A. Hokanson, Chao Chen, Julia Garcia Perez, Alevtina Pavlenco, Lynda Ploder, Alexander U. Singer, Michael D. L. Suits, Sunil Bhakta, Jagath R. Junutula, Jarrett J. Adams, Sachdev S. Sidhu   +12 more
wiley   +1 more source

Referente de Pensamiento eje 4: Salud Ambiental I ¿qué son las tecnologías alternativas y cómo pueden ser implementadas en busca de mejores condiciones de salud ambiental para el país?

, 2018
En este eje se mostrará que para contribuir al mejoramiento de la salud ambiental en el país existen múltiples acciones entre las cuales está el fortalecimiento de la parte intersectorial tendiente a crear un ambiente sostenible y favorable para la salud;
Erazo, Jenny
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