A comparison of three replication strategies in complex multicellular organisms: Asexual replication, sexual replication with identical gametes, and sexual replication with distinct sperm and egg gametes [PDF]
This paper studies the mutation-selection balance in three simplified replication models. The first model considers a population of organisms replicating via the production of asexual spores. The second model considers a sexually replicating population that produces identical gametes.
arxiv +1 more source
A deep-learning approach to early identification of suggested sexual harassment from videos [PDF]
Sexual harassment, sexual abuse, and sexual violence are prevalent problems in this day and age. Women's safety is an important issue that needs to be highlighted and addressed. Given this issue, we have studied each of these concerns and the factors that affect it based on images generated from movies.
arxiv
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro+12 more
wiley +1 more source
Embryonic cranial cartilage defects in the Fgfr3Y367C/+ mouse model of achondroplasia
Abstract Achondroplasia, the most common chondrodysplasia in humans, is caused by one of two gain of function mutations localized in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) leading to constitutive activation of FGFR3 and subsequent growth plate cartilage and bone defects.
Susan M. Motch Perrine+9 more
wiley +1 more source
Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study
Abstract Objective Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic ...
Ahmed Y. Azzam+13 more
wiley +1 more source
Assessment of concurrent neoplasms and a paraneoplastic association in MOGAD
Abstract Cases of myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) co‐occurring with neoplasms have been reported. In this international, retrospective cohort study in South Korea and the USA, 16 of 445 (3.6%) patients with MOGAD had concurrent neoplasm within 2 years of MOGAD onset, resulting in a standardized incidence ...
Young Nam Kwon+24 more
wiley +1 more source
Dónde estamos: Segmento del libro ¨Obstetricia y ciencia¨
En los países donde existen las obstetras (midwife), la profesión de obstetricia (midwifery profession) se encuentra en una encrucijada histórica, debido al carácter de la sociedad contemporánea, nuevas tecnologías y los cambios en los sistemas de salud.
Diana Alegría Delgado+3 more
doaj
ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression
Abstract Objective We performed a pilot screen to assess the utility of the NULISA™ (Nucleic‐acid‐Linked Immuno‐Sandwich Assay) platform in the identification of amyotrophic lateral sclerosis (ALS) biomarkers. Methods Plasma from 86 individuals (48 ALS, 18 asymptomatic C9orf72 repeat expansion carriers (AsymC9), and 20 healthy controls) was analyzed ...
Eleanor V. Thomas+10 more
wiley +1 more source
Objectives. Evaluate the efficiency of the enzyme-linked immunoelectrotransfer blot test (EITB) for the detection of human cysticercosis using purified native antigen mix from cysticercus fluid of Taenia solium. Material and methods.
Eduardo Ayala-Sulca+1 more
doaj +1 more source
Construcción de una batería para la evaluación de la salud sexual de los/as niños/as y adolescentes*
La salud sexual en la infancia y en la adolescencia constituye una prioridad dado el importante impacto que esta ejerce en su salud global. Sin embargo, no existe un fuerte consenso sobre los indicadores que determinan el poseer una buena o una mala ...
Olga Fernández García+4 more
doaj +1 more source