Results 111 to 120 of about 397,104 (186)

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Real-world outcomes of patients receiving salvage therapies for immune checkpoint inhibitor-resistant Merkel cell carcinoma: a rationale for future clinical trials. [PDF]

J Immunother Cancer
Ch'en PY, Zhang Y, Hippe DS, Akaike T, Miller NJ, Church C, Lachance K, Finberg A, Gooley T, Hall E, Bhatia S, Nghiem P.   +11 more
europepmc   +1 more source

Improving the Robustness of Visual Teach‐and‐Repeat Navigation Using Drift Error Correction and Event‐Based Vision for Low‐Light Environments

Advanced Robotics Research, EarlyView.
Visual teach‐and‐repeat (VTR) navigation allows robots to learn and follow routes without building a full metric map. We show that navigation accuracy for VTR can be improved by integrating a topological map with error‐drift correction based on stereo vision.
Fuhai Ling, Ze Huang, Tony J. Prescott
wiley   +1 more source

Lasker~Bloomberg Public Service Award to Michael J. Fox: The challenge of Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Schekman R.
europepmc   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Choosing Wisely. [PDF]

J Gen Intern Med
Hinton S.
europepmc   +1 more source

Dual‐Mode Gripper With Suction and Shape‐Adaptive Freezing Grasps

Advanced Robotics Research, EarlyView.
This study presents a dual‐mode robotic gripper that combines vacuum suction with a shape‐adaptive freezing grasp. The freezing mode uses a compliant rubber membrane, a sprayed water layer, and dry‐ice powder to generate ice‐mediated adhesion while conforming to complex geometries.
Takuma Yanagisawa, Toshihiro Nishimura, Yosuke Suzuki, Tokuo Tsuji, Tetsuyou Watanabe   +4 more
wiley   +1 more source

Particle Therapy Co-Operative Group Consensus Statement on Reirradiation With Proton Therapy for Prostate Cancer. [PDF]

Int J Part Ther
Hasan S, Shen X, Giap H, Patel S, Hyde C, Deville C, Gray J, Simone CB, Mendenhall NP, Choi S, Bryant CM.   +10 more
europepmc   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Screening of purine nucleoside analogues against intracellular Toxoplasma gondii. [PDF]

Int J Parasitol Drugs Drug Resist
Elati HAA, Van Calenbergh S, Sheiner L, de Koning HP.   +3 more
europepmc   +1 more source