Results 191 to 200 of about 499,794 (257)

Real-world outcomes of talimogene laherparepvec as salvage therapy for advanced melanoma. [PDF]

J Immunother Cancer
Yamada MM, Chandrasekhar S, Gooley TA, Chen RE, Doolittle-Amieva C, Ansstas G, Bhatia S, Hall ET, Nghiem PT, Park SY, Chen DY.   +10 more
europepmc   +1 more source

Winnowing Derivative Suits Through Attorneys Fees [PDF]

, 1984
Conard, A. F.
core   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Improved overall survival with checkpoint inhibition and allogeneic transplantation in relapsed Hodgkin lymphoma. [PDF]

Blood Adv
Tabbara N, Zahurak M, Sterling CH, Trutzer IM, Jedrych J, Swinnen LJ, Fuchs EJ, Bolaños-Meade J, Wagner-Johnston N, Jones RJ, Ambinder RF, Varadhan R, Paul S.   +12 more
europepmc   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Development and Validation of a Multimodal Artificial Intelligence-derived Digital Pathology-based Biomarker Predicting Metastasis Among Patients with Biochemical Recurrence After Radical Prostatectomy in NRG/RTOG Trials. [PDF]

Eur Urol
Morgan TM, Ren Y, Tang S, Zwerink W, Chen E, Mitani A, Huang HC, Simko JP, DeVries S, Pollack A, Wilke D, Martin AG, Balogh AG, Michalski JM, Greenberg MJ, Efstathiou JA, Bahary JP, Ross AE, Esteva A, Royce TJ, Nguyen PL, Hoffman KE, Sandler HM, Tran PT, Pugh SL, Feng FY, Spratt DE.   +26 more
europepmc   +1 more source

Environmental Law at Maryland, no. 20, winter-spring 2005 [PDF]

, 2005

core   +1 more source

Direct Photocurrent Detection of Optical Vortex Based on the Orbital Photo Galvanic Effect: Progress, Challenge, and Perspective

Advanced Science, EarlyView.
Direct orbital angular momentum (OAM) detection through the orbital photogalvanic effect offers a scalable route for integrated optoelectronics. This perspective evaluates symmetry‐driven material selection and demonstrates how electrode matrices enable the resolution of complex, mixed OAM modes.
Jinluo Cheng, Dehong Yang, Weiming Wang, Chang Xu, Zipu Fan, Dong Sun   +5 more
wiley   +1 more source

Plasma nicotinamide adenine dinucleotide pathway depletion is linked to diastolic dysfunction in patients with advanced chronic liver disease. [PDF]

Cardiovasc Res
Gill M, O'Sullivan JF, Guglielmi G, Slaughter E, Liu RP, Hunyor I, Moss S, McGrady M, Wilcox I, McCaughan GW, Majumdar A.   +10 more
europepmc   +1 more source