Results 131 to 140 of about 64,166 (267)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Phytochemical investigation of Salvia Transsylvanica, Salvia Glutinosa, and Salvia Officinalis from Romania and their bioactivities

, 2019
In the Romanian traditional medicine sage species are used as remedies for coughs, rheumatism, inflammatory and bacterial diseases, as well as antidiabetic remedies. In this study, an HPLC method was applied for determination of 22 phenolic compounds in extracts of S. glutinosa, S. transsylvanica, and S. officinalis.
A. Mocan, A. Pop, I. Fizeșan, A. Diuzheva, S. Carradori, M. Locatelli, M. Soković, G. Zengin, G. Crișan   +8 more
openaire   +2 more sources

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Metabarcoding of Pollen Carried by Syrphids Reveals Novel Plant–Pollinator Interactions in a Protected Natural Area and Agricultural Sites

Entomologia Experimentalis et Applicata, EarlyView.
Using DNA metabarcoding, this study investigates pollen transported by syrphids (Syrphidae) in the Dolomiti Bellunesi National Park and agricultural sites in Northern Italy. The analysis reveals a high diversity of visited plant taxa, including previously undocumented plant–pollinator interactions.
Serena Magagnoli, Daniele Sommaggio, Claudio Ratti, Riccardo Baroncelli, Andrea Menicucci, Enrico Vettorazzo, Giovanni Burgio   +6 more
wiley   +1 more source

THE EXPECTORANT ACTIVITY RESEARCH OF PHYTOPREPARATIONS OF THE WILD AND CULTIVATED SPECIES OF THE SALVIA L. GENUS

Кубанский научный медицинский вестник, 2015
The expectorant activity research of infusions and water-soluble polysaccharide complexes of Salvia genus plants was carried out on the model of studying of motor function of the ciliated epithelium of frog esophagus.
V. N. Bubenchikova, Y. A. Kondratova, N. V. Chetverikova   +2 more
doaj  

Mapping wild bee diversity and flower use for an effective conservation of the Doñana biodiversity hotspot

Insect Conservation and Diversity, EarlyView.
We compiled the first checklist of wild bees in Doñana Protected Area, documenting 385 species, including three vulnerable and one endangered species listed in the Red List. Bee species exhibit diverse floral preferences, highlighting the need to incorporate plant–pollinator interactions and the role of plants in conservation and management strategies ...
Francisco P. Molina, Nerea Montes‐Pérez, Luis Villagarcía, Ignasi Bartomeus   +3 more
wiley   +1 more source

Fluoride‐Free Mouthwashes Available Over‐The‐Counter in the US‐An Overview

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Fluoride‐free mouthwashes (FFM) are commonly used by patients for a variety of cosmetic and/or therapeutic reasons. The purpose of this study was to investigate the composition and purposes of FFM available over‐the‐counter in the US.
Astrid C. Valdivia‐Tapia, Jaime A. Cury, Antonio P. Ricomini‐Filho, Frank Lippert   +3 more
wiley   +1 more source

Content Determination and Chemical Clustering Analysis of Tanshinone and Salvianolic Acid in Salvia spp.

Metabolites
Salvia miltiorrhiza is one of the famous traditional Chinese medicines for treating cardiovascular and cerebrovascular diseases. Tanshinone and phenolic acids are the main active compounds of Salvia miltiorrhiza, whereas the distribution patterns of the ...
Feiyan Wang, Yufeng Bao, Furui Yang, Lu Yuan, Xinchun Han, Yanbo Huang, Yukun Wei, Lei Zhang, Zongqi Yang, Dongfeng Yang   +9 more
doaj   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Local Sodium Tanshinone IIA Sulfonate Attenuates Periodontal Bone Loss by Modulating Inflammatory, Immune and Osteoclastogenic Signalling

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate whether local administration of sodium tanshinone IIA sulfonate (STS) modulates periodontal inflammation, alveolar bone loss, immune response and bone remodelling–related signalling pathways in a ligature‐induced murine model of periodontitis.
Rafael Scaf de Molon, Raquel Mantuaneli Scarel‐Caminaga, François Isnaldo Dias Caldeira, Edilson Ervolino, Erica Dorigatti de Avila, Paula Aboud Barbugli, Gabriela Ezequiel Oliveira, Joao Pedro Franco‐Moura, Leticia Helena Theodoro, Joni Augusto Cirelli, Sotirios Tetradis, Alpdogan Kantarci   +11 more
wiley   +1 more source