Results 31 to 40 of about 2,499,224 (321)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

In Vitro Effect of Neopterin on Splenic Mast Cell Development in Senescence Accelerated Mice (SAM)

Pteridines, 2007
Neopterin is produced by monocytes and is a useful biomarker of inflammatory responses. We found that neopterin enhances granulopoiesis, but suppresses B-lymphopoiesis triggered by the positive- and negative regulations of cytokines produced by stromal ...
Harada Tomonori, Tsuboi Isao, Yuda Miyuki, Wakasugi Kazunori, Aizawa Shin   +4 more
doaj   +1 more source

Correlation Analysis of Antioxidant Activities with Tannin, Total Flavonoid, and Total Phenolic Contents of Nutmeg (Myristica fragrans Houtt) Fruit Precipitated by Egg white

Borneo Journal of Pharmacy, 2021
The nutmeg (Myristica fragrans) flesh extract has a strong antioxidant activity. Therefore, M. fragrans flesh can be developed for functional drinks which are sources rich in antioxidants good for the prevention and treatment of diseases such as cancer ...
Irma Antasionasti, Olvie Syenni Datu, Utami Sasmita Lestari, Surya Sumantri Abdullah, Imam Jayanto   +4 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Increasing the Efficiency of Mobile Robot Navigation Using Slam with Several Advanced Algorithms and Filters

Journal of Mechanical Engineering
Several algorithms such as A*, Dijkstra, SLAM (Simultaneous Localisation and Mapping) and APF (Artificial Potential Field) were used in this study to create local maps, plan the shortest path, and localize mobile robots.
Pajaziti Arbnor, Bajrami Xhevahir, Fandaj Arjanit   +2 more
doaj   +1 more source

SISTEM AKUNTANSI MANAJEMEN, GAYA KEPEMIMPINAN, DAN DESENTRALISASI SEBAGAI DETERMINAN KINERJA MANAJERIAL [PDF]

Jurnal Akuntansi Multiparadigma, 2014
: Management Accounting System, Leadership Style, and Decentralization as Determinants of Managerial Performance. The purpose of this study is to examine whether Management Accounting System (MAS) can mediate the effect of leadership style and ...
Andika Rante, Rosidi, Ali Djamhuri
doaj  

SAMplus: adaptive optics at optical wavelengths for SOAR

, 2018
Adaptive Optics (AO) is an innovative technique that substantially improves the optical performance of ground-based telescopes. The SOAR Adaptive Module (SAM) is a laser-assisted AO instrument, designed to compensate ground-layer atmospheric turbulence ...
Andrade, D., Domingues, M., Faes, D. M., Mello, A., Quint, B. C., Santos, J. B., Tokovinin, A., Vieira, T.   +7 more
core   +1 more source

'What are we doing when we read?' - adult literacy learners' perceptions of reading [PDF]

, 2009
This article presents the results of a qualitative study into how adult literacy learners perceive reading. Individual interviews and focus groups were used to ask thirty-seven adult literacy learners at a London further education college what reading is.
Duncan, Sam
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source