Embedded-deep-learning-based sample-to-answer device for on-site malaria diagnosis [PDF]
Improvements in digital microscopy are critical for the development of a malaria diagnosis method that is accurate at the cellular level and exhibits satisfactory clinical performance.
Chae Yun Bae +18 more
doaj +2 more sources
Sample-to-answer direct real-time PCR detection of Anaplasma phagocytophilum, Ehrlichia spp., and Babesia spp. infections in whole-blood specimens [PDF]
Emerging tick-borne illnesses, such as anaplasmosis, babesiosis, or ehrlichiosis, are caused by obligate intracellular pathogens that have clinically comparable presentations.
Georgia Colasante +3 more
doaj +2 more sources
A fully integrated sample-to-answer diagnostic platform enables rapid quantification of post-transplant infection at the point-of-care [PDF]
Opportunistic infections after organ transplantation require frequent monitoring over years. However, current diagnostic tests are inaccessible to patients in resource-limited settings.
Pengkun Yin +8 more
doaj +2 more sources
Detection of clinically relevant Candida species from positive blood cultures using a novel sample-to-answer molecular assay [PDF]
We evaluated the diagnostic performance of the newly developed MoiM Dx Candida 9-plex (MoiM) assay for the detection of Candida species from positive blood cultures and compared the results with those obtained from the BIOFIRE Blood Culture ...
Bosung Park +8 more
doaj +2 more sources
Detection of SARS-CoV-2 VOC-Omicron using commercial sample-to-answer real-time RT-PCR platforms and melting curve-based SNP assays [PDF]
Summary: Objectives: The World Health Organization (WHO) had designated the SARS-CoV-2 lineage B.1.1.529 as the new Variant of Concern Omicron (VOC-Omicron) on 26th November 20211.
Brian H.M. Sit +9 more
doaj +2 more sources
Sample-to-answer, extraction-free, real-time RT-LAMP test for SARS-CoV-2 in nasopharyngeal, nasal, and saliva samples: Implications and use for surveillance testing [PDF]
The global COVID-19 pandemic has highlighted the need for rapid, accurate and accessible nucleic acid tests to enable timely identification of infected individuals. We optimized a sample-to-answer nucleic acid test for SARS-CoV-2 that provides results in
Kathryn A. Kundrod +13 more
doaj +3 more sources
Correction: A fully automated sample-to-answer PCR system for easy and sensitive detection of dengue virus in human serum and mosquitos. [PDF]
[This corrects the article DOI: 10.1371/journal.pone.0218139.].
PLOS ONE Staff
doaj +2 more sources
Demonstration of a fast and easy sample-to-answer protocol for tuberculosis screening in point-of-care settings: A proof of concept study. [PDF]
We sought to develop a smooth and low cost sample preparation and DNA extraction protocol, streamlined with a ready-to-use qPCR in a portable instrument to overcome some of the existing hurdles.
Nasir Ali +4 more
doaj +2 more sources
Sample-to-Answer Robotic ELISA. [PDF]
Enzyme-linked immunosorbent assays (ELISA), as one of the most used immunoassays, have been conducted ubiquitously in hospitals, research laboratories, etc.
Zhou C +7 more
europepmc +2 more sources
Mycoplasma pneumonia (MP) is a common respiratory infection generally treated with macrolides, but resistance mutations against macrolides are often detected in mycoplasma pneumoniae in China.
Anyan Wang +7 more
doaj +1 more source

