Results 1 to 10 of about 211,147 (118)

In Vitro Diagnostic Assay to Detect SARS-CoV-2-Neutralizing Antibody in Patient Sera Using Engineered ACE-2 Mini-Protein [PDF]

Viruses, 2022
The recent development and mass administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccines allowed for disease control, reducing hospitalizations and mortality.
Bruna Andersen Pereira de Jesus, Anderson Albino Gomes, Alex E. Clark, Tayse Andrade Rodrigues, Melissa Ledgerwood-Lee, Westley Van Zant, Howard Brickner, Meiqiao Wang, David L. Blum, Maria B. Cassera, Aaron F. Carlin, Eliah S. Aronoff-Spencer, Gustavo Felippe da Silva, Maria de Lourdes Borba Magalhães, Partha Ray   +14 more
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PD-L1 in pancreatic ductal adenocarcinoma: a retrospective analysis of 373 Chinese patients using an in vitro diagnostic assay [PDF]

Diagnostic Pathology, 2018
Background Programmed death ligand 1 (PD-L1) has shown potential as a therapeutic target in numerous solid tumors. Its prognostic significance has also been established in pancreatic ductal adenocarcinoma (PDAC).
Xiaolong Liang, Jian Sun, Huanwen Wu, Yufeng Luo, Lili Wang, Junliang Lu, Zhiwen Zhang, Junchao Guo, Zhiyong Liang, Tonghua Liu   +9 more
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In-vitro synthesis of RNA fragments specifying envelope protein gene and RdRp gene of SARS-CoV-2 as positive standards for molecular diagnosis tests

Vietnam Journal of Science, Technology and Engineering, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19), has rapidly spread through the entire world and has become the worst pandemic from December 2019 until now.
Hang Thi Thu Dinh, Mai Ngoc Nguyen, Su Xuan Hoang   +2 more
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Clinical Evaluation of an Immunochromatographic-Based IgM/IgG Antibody Assay (GenBody™ COVI040) for Detection of Antibody Seroconversion in Patients with SARS-CoV-2 Infection

Diagnostics, 2021
There is a need for accurate diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease (COVID-19).
Doyeong Kim, Jihoo Lee, Jyotiranjan Bal, Chom-Kyu Chong, Jong Ho Lee, Hyun Park   +5 more
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CircTENM3 inhibites tumor progression via the miR-558/RUNX3 axis in prostate cancer

Journal of Translational Medicine, 2023
Background Prostate cancer (PCa) is currently acknowledged as the second most widespread cancer among men worldwide. Yet, the lack of dependable diagnostic biomarkers and therapeutic targets has presented considerable hurdles to the progression of ...
Lingxiang Lu, Fei Wang, Jianchun Chen, Chunchun Zhao, Shuai Guo, Da Dong, Minjun Jiang, Yuhua Huang   +7 more
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Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma

Cancer Cell International, 2021
Background Lung cancer is the most common malignant tumor. Identification of novel diagnostic and prognostic biomarkers for lung cancer is a key research imperative.
Jiayu Ma, Xiaochuan Chen, Mingqiang Lin, Zhiping Wang, Yahua Wu, Jiancheng Li   +5 more
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MicroRNA-375-3p is implicated in carotid artery stenosis by promoting the cell proliferation and migration of vascular smooth muscle cells

BMC Cardiovascular Disorders, 2021
Background Atherosclerosis is the main cause of carotid artery stenosis (CAS) which mostly occurs in the elderly. In this paper, the expression level of miR-375-3p in asymptomatic CAS patients and its diagnostic value for asymptomatic CAS were ...
Yuxia Yin, Zhen Cheng, Xiaoling Fu, Shishun Ji   +3 more
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Junctional Adhesion Molecule-Like Protein Promotes Tumor Progression and Metastasis via p38 Signaling Pathway in Gastric Cancer

Frontiers in Oncology, 2021
Junctional adhesion molecule-like protein (JAML), a newly discovered junctional adhesion molecule (JAM), mediates the adhesion and migration processes of various immune cells and endothelial/epithelial cells, ultimately regulating inflammation reaction ...
Yuying Fang, Yuying Fang, Jianmin Yang, Guohong Zu, Guohong Zu, Changsheng Cong, Changsheng Cong, Shuai Liu, Shuai Liu, Fei Xue, Shuzhen Ma, Shuzhen Ma, Jie Liu, Jie Liu, Yuping Sun, Yuping Sun, Meili Sun, Meili Sun, Meili Sun   +18 more
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Generation of Functional Cardiomyocytes from Human Gastric Fibroblast-Derived Induced Pluripotent Stem Cells

Biomedicines, 2021
Coronary artery diseases are major problems of the world. Coronary artery disease patients frequently suffer from peptic ulcers when they receive aspirin treatment.
Chih-Hsien Wu, Hsuan-Hwai Lin, Yi-Ying Wu, Yi-Lin Chiu, Li-Yen Huang, Cheng-Chung Cheng, Chung-Chi Yang, Tsung-Neng Tsai   +7 more
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Immunomagnetic DNA Aptamer Assay

BioTechniques, 2001
DNA aptamers, oligonucleotides with antibody-like binding properties, are easy to manufacture and modify. As a class of molecules, they represent the biggest revolution to immunodiagnostics since the discovery of monoclonal antibodies.
Phil D. Rye, Kjell Nustad
doaj   +1 more source