Results 31 to 40 of about 115,167,710 (246)

Performance of the LIAISON PLEX yeast blood culture assay for identifying 16 invasive fungal pathogens in blood cultures

Journal of Clinical Microbiology
Fungi frequently cause potentially life-threatening bloodstream infections, particularly in immunocompromised and hospitalized individuals. Molecular methods can allow earlier pathogen identification for faster optimization of appropriate therapy.
Christopher L. Emery, Neelam Dhiman, Siu-Kei Chow, Gwyn Peterson, Paul Granato, Brian Bernier, Janet Farhang   +6 more
doaj   +1 more source

Highly sensitive and accurate detection of C-reactive protein by CdSe/ZnS quantum dot-based fluorescence-linked immunosorbent assay

Journal of Nanobiotechnology, 2017
Background The conventional and widely used enzyme-linked immunosorbent assays (ELISA), due to specificity and high-sensitivity, were suitable in vitro diagnosis.
Yanbing Lv, Ruili Wu, Kunrui Feng, Jinjie Li, Qing Mao, Hang Yuan, Huaibin Shen, Xiangdong Chai, Lin Song Li   +8 more
doaj   +1 more source

RETRACTED: Circular RNA hsa_circ_0013958 Functions as an Oncogenic Gene Through Modulating miR-532-3p/WEE1 Axis in Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Backgroundcirc0013958 was identified as a biomarker, which can be used for the diagnosis and screening of lung cancer. However, the role of circ0013958 in hepatocellular carcinoma (HCC) remains unclear.MethodsIn our study, quantitative real-time ...
Tao Ma, Yue Ma, Yongjun Du, Zhongheng Wei, Jianchu Wang, Yufu Jun, Fenqiang Xiao   +6 more
doaj   +1 more source

Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive study. [PDF]

, 2012
BACKGROUND: The diagnostic accuracy of sputum smear microscopy and routine chest radiology for HIV-associated tuberculosis is poor, and culture-based diagnosis is slow, expensive, and is unavailable in most resource-limited settings.
Vogt, Monica, Kerkhoff, Andrew D, Monica Vogt, Lawn, Stephen D, Robin Wood, Andrew D Kerkhoff, Stephen D Lawn, Wood, Robin   +7 more
core   +1 more source

Enhancing ELISA Sensitivity: From Surface Engineering to Synthetic Biology

Biosensors
Accurate and sensitive detection of protein biomarkers is critical for advancing in vitro diagnostics (IVD), yet conventional enzyme-linked immunosorbent assays (ELISA) often fall short in terms of sensitivity compared to nucleic acid-based tests ...
Hye-Bin Jeon, Dong-Yeon Song, Yu Jin Park, Dong-Myung Kim   +3 more
doaj   +1 more source

The performance of the SEPT9 gene methylation assay and a comparison with other CRC screening tests: A meta-analysis

Scientific Reports, 2017
The SEPT9 gene methylation assay is the first FDA-approved blood assay for colorectal cancer (CRC) screening. Fecal immunochemical test (FIT), FIT-DNA test and CEA assay are also in vitro diagnostic (IVD) tests used in CRC screening.
Lele Song, Jia Jia, Xiumei Peng, Wenhua Xiao, Yuemin Li   +4 more
doaj   +1 more source

Development of a One-Step SYBR Green I Real-Time RT-PCR Assay for the Detection and Quantitation of Araraquara and Rio Mamore Hantavirus

Viruses, 2013
Hantaviruses are members of the family Bunyaviridaeandare an emergingcause of diseaseworldwidewithhighlethalityin the Americas. In Brazil, thediagnosis forhantaviruses is basedonimmunologictechniquesassociatedwithconventionalRT-PCR.Anovelone ...
Luiz Tadeu Moraes Figueiredo, Michelly de Pádua, Aline Rafaela da Silva Rodrigues Machado, Alex Martins Machado, William Marciel de Souza   +4 more
doaj   +1 more source

Universal single-probe RT-PCR assay for diagnosis of dengue virus infections. [PDF]

PLoS Neglected Tropical Diseases, 2014
Dengue is a mosquito-borne viral disease that has become more prevalent in the last few decades. Most patients are viremic when they present with symptoms, and early diagnosis of dengue is important in preventing severe clinical complications associated ...
Erik Alm, Birgitta Lesko, Gunnel Lindegren, Clas Ahlm, Sandra Söderholm, Kerstin I Falk, Nina Lagerqvist   +6 more
doaj   +1 more source

Serodiagnosis of Echinococcus spp. infection: explorative selection of diagnostic antigens by peptide microarray [PDF]

, 2010
BACKGROUND: Production of native antigens for serodiagnosis of helminthic infections is laborious and hampered by batch-to-batch variation. For serodiagnosis of echinococcosis, especially cystic disease, most screening tests rely on crude or purified ...
Maag, Eva, List, C, List, C., Gottstein, Bruno, Gottstein Bruno, Felger Ingrid, Felger, Ingrid, Qi, W, Gottstein, B., Ingrid Felger, Maag Eva, Qi Weihong, Müller, N., Felger, I, Müller, Norbert, Norbert Müller, List, Claudia, Gottstein, B, Müller Norbert, Felger, I., Maag, E., Müller, N, Qi, W., Eva Maag, Bruno Gottstein, List Claudia, Claudia List, Maag, E, Qi, Weihong, Weihong Qi   +29 more
core   +2 more sources

Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]

, 2001
Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht, Kastenbauer, Ernst R., Gamarra, Fernando, Kleinsasser, Norbert H., Harréus, Ulrich A., Huber, Rudolf M., Wallner, Barbara C., Juchhoff, Jutta   +7 more
core   +1 more source