Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay [PDF]
There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment.
Luker, George W.
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High diagnostic yield of tuberculosis from screening urine samples from HIV-infected patients with advanced immunodeficiency using the Xpert MTB/RIF assay. [PDF]
: ABSTRACT:: We determined the diagnostic yield of the Xpert MTB/RIF assay for tuberculosis (TB) when testing small volumes of urine from ambulatory HIV-infected patients prior to starting antiretroviral therapy (ART) in South Africa.
Vogt, M, Kerkhoff, AD, Wood, R, Lawn, SD
core +5 more sources
GradinaruLab/in-vitro-transduction-assay: Science Advances Publication
This code contains notebooks and files to analyze in vitro images for transduction and ...
David Goertsen
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Development of an in vitro drug sensitivity assay based on newly excysted larvae of Echinostoma caproni [PDF]
Echinostomiasis is one of the major food-borne trematodiases and the species Echinostoma caproni serves as a useful model for trematocidal drug discovery. The current in vitro drug sensitivity assay uses adult E.
Gordana Panic +5 more
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Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae [PDF]
Trichuriasis represents a major public health problem in the developing world and is regarded as a neglected disease. Albendazole and mebendazole, the two drugs of choice against trichuriasis display only moderate cure rates, hence alternative drugs are ...
Jennifer Keiser +5 more
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Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies. [PDF]
Detection of the Mycobacterium tuberculosis cell wall antigen lipoarabinomannan (LAM) in urine permits diagnoses of tuberculosis (TB) to be made in HIV-infected patients with advanced immunodeficiency.
Kerkhoff, Andrew D +23 more
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Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula [PDF]
BACKGROUND: The development of novel antischistosomal drugs is crucial, as currently no vaccine and only a single drug is available for the treatment of schistosomiasis.
Ingram, K. +11 more
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Lipoarabinomannan in urine during tuberculosis treatment: association with host and pathogen factors and mycobacteriuria. [PDF]
BACKGROUND: Detection of lipoarabinomannan (LAM), a Mycobacterium tuberculosis (Mtb) cell wall antigen, is a potentially attractive diagnostic. However, the LAM-ELISA assay has demonstrated variable sensitivity in diagnosing TB in diverse clinical ...
Vogt, Monica +24 more
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Background Light microscopy and antigen-based rapid diagnostic tests are the primary diagnostic tools for detecting malaria, although being labour-intensive and frequently challenged by lack of personnel’s experience and low levels of parasite density ...
Anne-Sophie De Koninck +5 more
doaj +1 more source
lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer
Background Abnormal expression of long non-coding RNAs (lncRNAs) has been found in almost all human tumors, providing numerous potential diagnostic biomarkers, prognostic biomarkers, and therapeutic targets.
Mu Xu +12 more
doaj +1 more source

