Results 31 to 40 of about 6,355,308 (199)

TLE1 as a key regulator of osimertinib resistance and EMT in lung adenocarcinoma: implications for prognosis and immunotherapy response

Hereditas
Background Acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) poses a considerable challenge for the long-term treatment of non-small cell lung cancer (NSCLC).
Na Chen, Tianlin Wang, Yi Li, Ruixia Zhang, Xiduan Wei, Zhenglu Wang   +5 more
doaj   +1 more source

High-throughput platform for label-free sorting of 3D spheroids using deep learning

Frontiers in Bioengineering and Biotechnology
End-stage liver diseases have an increasing impact worldwide, exacerbated by the shortage of transplantable organs. Recognized as one of the promising solutions, tissue engineering aims at recreating functional tissues and organs in vitro.
Claudia Sampaio da Silva, Claudia Sampaio da Silva, Julia Alicia Boos, Jonas Goldowsky, Manon Blache, Noa Schmid, Tim Heinemann, Christoph Netsch, Francesca Luongo, Stéphanie Boder-Pasche, Gilles Weder, Alba Pueyo Moliner, Roos-Anne Samsom, Ary Marsee, Kerstin Schneeberger, Ali Mirsaidi, Bart Spee, Thomas Valentin, Andreas Hierlemann, Vincent Revol   +19 more
doaj   +1 more source

Mosses (Bryophyta) of the Kostomuksha State Nature Reserve, Russia

Nature Conservation Research: Заповедная наука, 2021
The Kostomuksha State Nature Reserve (KSNR) is located in northwestern Russia, in the Republic of Karelia (hereinafter – Karelia), near the Finnish border. It has an area of 492.76 km2.
Margarita A. Boychuk
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

ESTIMATION OF THE COLLECTION RICE ACCORDING TO RESISTANCE TO CEREAL APHID

Зерновое хозяйство России, 2019
Ordinary cereal aphid causes great damage to rice plants in the Rostov region and the Krasnodar Territory. Its harmful effects can be limited with the help of plant genetic resistance.
P. I. Kostylev, E. V. Krasnova, E. E. Radchenko, T. L. Kuznetsova, M. A. Chumakov   +4 more
doaj   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

ESTIMATION OF ECONOMIC AND BIOLOGICAL TRAITS OF ALFALFA COLLECTION SAMPLES IN THE ROSTOV REGION

Зерновое хозяйство России, 2019
To stimulate livestock production increase, it is necessary to improve the production of high-quality feed with high protein percentage. The purpose can be achieved by an increase of sown area for perennial leguminous herbs and, in particular, alfalfa ...
S. А. Ignatiev, А. А. Regidin
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

LRP-DS: Lightweight RepPoints with Decoupled Sampling Point Set

Applied Sciences, 2021
Most object detection methods use rectangular bounding boxes to represent the object, while the representative points network (RepPoints) employs a point set to describe the object. The RepPoints can provide more fine-grained localization and facilitates
Jinchao Wang, Libo Weng, Fei Gao
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source