Results 81 to 90 of about 14,502,685 (316)
An adaptive two-sample test for high-dimensional means
SUMMARY Several two-sample tests for high-dimensional data have been proposed recently, but they are powerful only against certain alternative hypotheses.
Gongjun Xu, Lifeng Lin, Peng Wei, W. Pan
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
In the present work, the manufacture of a Cu-9Al-3Ag alloy was carried out easily through a green molding process. After dimensioning and slitting, the alloy samples were subjected to quenching, normalizing, and annealing heat treatments, to exert phase ...
Daniel Flores-Sanchez +5 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Improved dimension dependence of a proximal algorithm for sampling
We propose a sampling algorithm that achieves superior complexity bounds in all the classical settings (strongly log-concave, log-concave, Logarithmic-Sobolev inequality (LSI), Poincaré inequality) as well as more general settings with semi-smooth or composite potentials.
Jiaojiao Fan, Bo Yuan, Yongxin Chen
openaire +3 more sources
Power Analysis and Sample Size Determination in Metabolic Phenotyping.
Estimation of statistical power and sample size is a key aspect of experimental design. However, in metabolic phenotyping, there is currently no accepted approach for these tasks, in large part due to the unknown nature of the expected effect.
B. Blaise +10 more
semanticscholar +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Determining WWW User's Next Access and Its Application to Pre-fetching [PDF]
World-Wide Web (WWW) services have grown to levels where significant delays are expected to happen. Techniques like pre-fetching are likely to help users to personalize their needs, reducing their waiting times. However, pre-fetching is only effective if
Cunha, Carlos R., Jaccoud, Carlos F.B.
core +1 more source
Characteristics of WAP traffic [PDF]
This paper considers the characteristics of Wireless Application Protocol (WAP) traffic. We start by constructing a WAP traffic model by analysing the behaviour of users accessing public WAP sites via a monitoring system.
Irvine, J., Ma, I.
core +3 more sources

