Results 131 to 140 of about 13,319,037 (325)

Sorbent-less dried blood spot microsampling

Advances in Sample Preparation
Dried blood spots (DBSs) are typically sampled on porous sorbents, which may retain analytes in their structure during DBS rehydration but also release various species into the eluates and contaminate them.
Miloš Dvořák, Sylvie Profousová, Pavel Kubáň   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Editorial SI EuSP2022

Advances in Sample Preparation, 2023
Elefteria Psillakis, Stig Pedersen-Bjergaard, Sibel Ozkan   +2 more
doaj   +1 more source

Hydrophobic and aromatic polymer nanofibers for a spin-filter micro solid phase extraction of polycyclic aromatic hydrocarbons in river water

Advances in Sample Preparation
The use of hydrophobic and aromatic polymer nanofibers as novel sorbents for extracting polycyclic aromatic hydrocarbons (PAHs) from river water has been evaluated.
Ewelina Czyz, Marie Štorková, Jakub Erben, Pavel Holec, František Švec, Dalibor Šatínský   +5 more
doaj   +1 more source

Sample Preparation for Phosphoproteomic Analysis of Circadian Time Series in Arabidopsis thaliana

, 2014
Johanna Krahmer, Matthew Hindle, Sarah F. Martin, Thierry Le Bihan, Andrew J. Millar   +4 more
openalex   +1 more source

Site-Specific Cryo-focused Ion Beam Sample Preparation Guided by 3D Correlative Microscopy [PDF]

, 2016
Jan Arnold, Julia Mahamid, Vladan Lučić, Alex de Marco, José‐Jesús Fernández, Tim Laugks, Tobias Mayer, Anthony A. Hyman, Wolfgang Baumeister, Jürgen M. Plitzko   +9 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Development of smart samplers and their comparison to dried serum spots for the analysis of growth hormone releasing hormone analogs using LCHRMS/MS

Advances in Sample Preparation
Growth hormone-releasing hormone (GHRH) analogs, including sermorelin, CJC-1295, and tesamorelin, are prohibited in sports due to their performance-enhancing potential.
Christina Johannsen, Anna Kha Tu Nguyen, Sasha Shabani, Inger Oulie, Siri Dørum, Yvette Dehnes, Leon Reubsaet, Trine Grønhaug Halvorsen   +7 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Nitrogen-rich covalent organic polymers for efficient solid phase extraction of nonsteroidal anti-inflammatory drugs from water samples

Advances in Sample Preparation
Non-steroidal anti-inflammatory drugs (NSAIDs) have received increasing attention owing to their ubiquitous occurrence in environmental water systems and adverse effects.
Yuqi Cheng, Jia Li, Xiaochen Xiu, Xinghua Teng, Wen Zhang, Lei Ji, Leilei Wang   +6 more
doaj   +1 more source