Results 101 to 110 of about 11,717,609 (299)
Sample Size Estimation in Clinical Trials
National Journal of Community MedicineSample size estimation remains as a cornerstone in the meticulous planning and execution of clinical trials, pivotal for ensuring studies possess the requisite statistical power to discern meaningful treatment effects.
Divyangkumar Patel
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Impact of Small Group Size on Neighborhood Influences in Multilevel Models [PDF]
Objective: Although there is a growing body of literature on sample size in multilevel or hierarchical modeling, few studies have examined the impact of group sizeMultilevel, Neighborhood, Body Weight, Obesity, Sample ...
Cohen, Deborah +6 more
core
Sample-Size Planning for Multivariate Data: A Raman-Spectroscopy-Based Example
, 2018 The goal of sample-size planning (SSP) is to determine the number of measurements needed for statistical analysis. This SSP is necessary to achieve robust and significant results with a minimal number of measurements that need to be collected.
Nairveen Ali (5866097) +9 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Sample Size and Saturation in PhD Studies Using Qualitative Interviews
Forum: Qualitative Social Research, 2010 A number of issues can affect sample size in qualitative research; however, the guiding principle should be the concept of saturation. This has been explored in detail by a number of authors but is still hotly debated, and some say little understood.
Mark Mason
doaj
Analyzing Sample Size in Information-Theoretic Models
MathematicsIn this paper, we delve into the complexities of information-theoretic models, specifically focusing on how we can model sample size and how it affects our previous findings.
D. Bernal-Casas, J. M. Oller
doaj +1 more source
A new web application for determining sample size in freedom-from-disease testing with imperfect tests [PDF]
Veterinary surveillance frequently requires study design for freedom-from-disease testing, specifying a sample size to balance higher statistical power with larger sample sizes against increased research and ethics costs, with the recognition that tests ...
Green, Darren
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source