Results 101 to 110 of about 4,409,426 (307)
Yield stress fluids method to determine the pore size distribution of a porous medium [PDF]
In this paper a new method is presented in order to determine the pore size distribution in a porous medium. This original technique uses the rheological properties of some non-Newtonian yield stress fluids flowing through the porous sample.
AMBARI, Abdelhak +2 more
core +1 more source
Gene expression prediction model - 49 Genotype-Tissue Expression (GTEx, v8) tissues. More details about the models could be found in Methods "Transcriptome-wide association studies across 49 human cell-types and tissues" in paper "Genetic imputation of ...
Xiaoguang Xu (17666223)
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sample-Size Planning for Multivariate Data: A Raman-Spectroscopy-Based Example
The goal of sample-size planning (SSP) is to determine the number of measurements needed for statistical analysis. This SSP is necessary to achieve robust and significant results with a minimal number of measurements that need to be collected.
Nairveen Ali (5866097) +9 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A new web application for determining sample size in freedom-from-disease testing with imperfect tests [PDF]
Veterinary surveillance frequently requires study design for freedom-from-disease testing, specifying a sample size to balance higher statistical power with larger sample sizes against increased research and ethics costs, with the recognition that tests ...
Green, Darren
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The effect of sample particle size on the determination of pore structure parameters in shales
The combination of low-pressure N-2 and CO2 adsorption could provide an effective approach for characterizing the pore structure of shales. Although gas adsorption methods generally do not destroy the pore structure during experimental process, sample ...
Zhang, Li +4 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

