Results 111 to 120 of about 12,763,770 (297)
Sample Size Estimation in Clinical Trials
National Journal of Community MedicineSample size estimation remains as a cornerstone in the meticulous planning and execution of clinical trials, pivotal for ensuring studies possess the requisite statistical power to discern meaningful treatment effects.
Divyangkumar Patel
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Effects of Class Size on Achievement of College Students [PDF]
In this paper we investigate the effects of class size on the achievements of a sample of college students enrolled at a middle-sized Italian public university.
Scoppa, Vincenzo, De Paola, Maria
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Sample Size and Saturation in PhD Studies Using Qualitative Interviews
Forum: Qualitative Social Research, 2010 A number of issues can affect sample size in qualitative research; however, the guiding principle should be the concept of saturation. This has been explored in detail by a number of authors but is still hotly debated, and some say little understood.
Mark Mason
doaj
Analyzing Sample Size in Information-Theoretic Models
MathematicsIn this paper, we delve into the complexities of information-theoretic models, specifically focusing on how we can model sample size and how it affects our previous findings.
D. Bernal-Casas, J. M. Oller
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
In the social sciences, researchers often want to learn something about a larger population by studying a smaller group of people, called a sample. This raises the practical question of how large that sample should be. If the sample is too small, the study may not provide reliable answers.
openaire +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Sample sizes for the SF-6D preference based measure of health from the SF-36: a practical guide [PDF]
Background Health Related Quality of Life (HRQoL) measures are becoming more frequently used in clinical trials and health services research, both as primary and secondary endpoints.
Walters, SJ, Brazier, JE
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