Results 111 to 120 of about 9,094,534 (319)

Sample size calculation in clinical research

Perspectives in Clinical Research
Calculation of sample size is an essential part of research study design since it affects the reliability and feasibility of the research study. In this article, we look at the principles of sample size calculation for different types of research studies.
Priya Ranganathan, Vishal Deo, C. S. Pramesh   +2 more
doaj   +1 more source

Weighted skewness and kurtosis unbiased by sample size and Gaussian uncertainties [PDF]

, 2014
Lorenzo Rimoldini
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Sample size determination in medical researches

مجله علمی دانشگاه علوم پزشکی کردستان, 2020
Background and Aim: One of the problems of the researchers at the start of the research is the estimation of sample size and selection of an appropriate sample of the population. Small sample size can damage research credibility and lead to loss of money
Daem Roshani, Bijan Nouri, Masoud Moradi
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Sample size in health research

New Zealand Medical Student Journal, 2021
Ari Samaranayaka, Claire Cameron, Robin Turner   +2 more
doaj   +1 more source

Appendix A. Threshold fitting rates for each method by sample size, slope of change, and environmental distribution.

, 2016
Jonathan P. Daily, Nathaniel P. Hitt, David R. Smith, Craig D. Snyder   +3 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Appendix A. A table of location, size, and observed vegetation type for eight sites burned by wildfire, and eight corresponding non-burned sites, in which individual lodgepole pines (N=2056) were sampled for degree of fire injury and attacks by Dendroctonus ponderosae throughout the Greater Yellowstone Ecosystem, USA.

, 2016
Erinn N. Powell, Philip A. Townsend, Kenneth F. Raffa   +2 more
openalex   +1 more source