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Sample size calculation in clinical research [PDF]

open access: yesPerspectives in Clinical Research
Calculation of sample size is an essential part of research study design since it affects the reliability and feasibility of the research study. In this article, we look at the principles of sample size calculation for different types of research studies.
Priya Ranganathan   +2 more
doaj   +5 more sources

Sample size calculation

open access: yesAmrita Journal of Medicine, 2023
In the chapter of the book titled "MZ Islam's Research Methodology", the focus is on the crucial aspect of sample size calculation, which plays a key role in designing robust research studies. The chapter outlines the importance of determining an appropriate sample size, as it directly affects the reliability, validity, and generalizability of research
S Saraswathy   +3 more
doaj   +9 more sources

Sample size calculation in clinical trial using R [PDF]

open access: yesJournal of Minimally Invasive Surgery, 2023
Since the era of evidence-based medicine, it has become a matter of course to use statistics to create objective evidence in clinical research. As an extension of this, it has become essential in clinical research to calculate the correct sample size to ...
Suyeon Park   +3 more
doaj   +3 more sources

Reporting Sample Size Calculation in Randomized Clinical Trials Published in 4 Orthodontic Journals [PDF]

open access: yesTurkish Journal of Orthodontics, 2021
Objective: The purpose of this study was to describe sample size calculations in randomized clinical trials (RCTs) published in 4 orthodontic journals.Methods:This cross-sectional study evaluated 142 RCTs published between 2015 and 2019 in the 4 journals
Marialicia Calderon-Augusto   +2 more
doaj   +3 more sources

Sample Size Calculation in Genetic Association Studies: A Practical Approach [PDF]

open access: yesLife, 2023
Genetic association studies, testing the relationship between genetic variants and disease status, are useful tools for identifying genes that grant susceptibility to complex disorders.
Cristina Politi   +3 more
doaj   +3 more sources

Principles of sample size calculation

open access: yesIndian Journal of Ophthalmology, 2010
In most areas in life, it is difficult to work with populations and hence researchers work with samples. The calculation of the sample size needed depends on the data type and distribution.
Gogtay Nithya
doaj   +4 more sources

Sample size calculation: Basic principles

open access: yesIndian Journal of Anaesthesia, 2016
Addressing a sample size is a practical issue that has to be solved during planning and designing stage of the study. The aim of any clinical research is to detect the actual difference between two groups (power) and to provide an estimate of the ...
Sabyasachi Das   +2 more
doaj   +4 more sources

Sample size calculations for indirect standardization [PDF]

open access: yesBMC Medical Research Methodology, 2023
Indirect standardization, and its associated parameter the standardized incidence ratio, is a commonly-used tool in hospital profiling for comparing the incidence of negative outcomes between an index hospital and a larger population of reference ...
Yifei Wang, Philip Chu
doaj   +4 more sources

Tips for troublesome sample-size calculation [PDF]

open access: yesKorean Journal of Anesthesiology, 2020
Properly set sample size is one of the important factors for scientific and persuasive research. The sample size that can guarantee both clinically significant differences and adequate power in the phenomena of interest to the investigator, without ...
Junyong In   +7 more
doaj   +5 more sources

Sample size calculation for phylogenetic case linkage. [PDF]

open access: yesPLoS Computational Biology, 2021
Sample size calculations are an essential component of the design and evaluation of scientific studies. However, there is a lack of clear guidance for determining the sample size needed for phylogenetic studies, which are becoming an essential part of ...
Shirlee Wohl   +2 more
doaj   +2 more sources

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