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Sample size calculation: Basic principles
Addressing a sample size is a practical issue that has to be solved during planning and designing stage of the study. The aim of any clinical research is to detect the actual difference between two groups (power) and to provide an estimate of the ...
Sabyasachi Das +2 more
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Sample size calculation in multi-centre clinical trials [PDF]
Background Multi-centre randomized controlled clinical trials play an important role in modern evidence-based medicine. Advantages of collecting data from more than one site are numerous, including accelerated recruitment and increased generalisability ...
Markus Harden, Tim Friede
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The research protocol V: The calculation of sample size
Sample size refers to the number of participants to be included in a research study. If the calculation is carried out properly, not only conclusions will be established with statistical support and the potential risks to the subjects included in the ...
Mario Enrique Rendón-Macías +1 more
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The Power of Sample Size Calculations
Abstract Researchers frequently come across sample size calculations in the scientific literature they read, in projects undertaken by their peers, and likely within their own work. However, despite its ubiquity, calculating a sample size is often perceived as a hurdle and not fully understood.
Rolf Groenwold +2 more
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Power and sample size calculation for stepped-wedge designs with discrete outcomes [PDF]
Background Stepped-wedge designs (SWD) are increasingly used to evaluate the impact of changes to the process of care within health care systems. However, to generate definitive evidence, a correct sample size calculation is crucial to ensure such ...
Fan Xia +3 more
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A practical approach to sample size calculation for fixed populations [PDF]
Researchers routinely compute desired sample sizes of clinical trials to control type-i and type-ii errors. While for many experimental designs sample size calculations are well-known, it remains an active area of research.
Maurits Kaptein
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Common errors in sample size calculation in clinical research: A focused critique [PDF]
Farzan Madadizadeh +2 more
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Sample Size Calculations [PDF]
The sample size is the number of patients or other experimental units that need to be included in a study to answer the research question. Pre-study calculation of the sample size is important; if a sample size is too small, one will not be able to detect an effect, while a sample that is too large may be a waste of time and money. Methods to calculate
Noordzij, M. +3 more
openaire +6 more sources

