Results 211 to 220 of about 8,978,019 (319)

Sample size justification in feasibility studies: moving beyond published guidance. [PDF]

Pilot Feasibility Stud
Montgomery R.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models - part 2: time-to-event outcomes. [PDF]

Diagn Progn Res
Riley RD, Collins GS, Archer L, Whittle R, Legha A, Kirton L, Dhiman P, Sadatsafavi M, Adderley NJ, Alderman J, Martin GP, Ensor J.   +11 more
europepmc   +1 more source

Towards site-independent calibration of in situ soil pH sensor data: Relevance of spatial and temporal proximity, sample size and data spread for calibration model performance

Sebastian Vogel, Mandy Gebbers, Ingmar Schröter, Wolfgang Schwanghart, Eric Bönecke, Jörg Rühlmann, Eckart Krämer, Robin Gebbers   +7 more
openalex   +1 more source

Sample Size Analysis for Asphalt Pavement Quality Control

, 1999
Brenda McCabe, Simaan AbouRizk, Jim Gavin   +2 more
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A nextflow pipeline for molecular quantitative trait loci mapping in small sample size datasets with an application in Atlantic salmon. [PDF]

BMC Genomics
Nguyen DT, Sandve SR, Lien S, Grønvold L.   +3 more
europepmc   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

CONTEST: A generalization of ONEST to estimate sample size for predictive augmented intelligence method validation studies. [PDF]

J Pathol Inform
Olson BK, Rosenthal JH, Kappedal RD, Olson NH.   +3 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source