Results 241 to 250 of about 12,763,770 (297)

Does Increasing Sample Size Inevitably Lead to Statistical Significance? Insights From a Monte Carlo Simulation Study for Medical Research Design. [PDF]

J Eval Clin Pract
Li M, Yang S, Wang Y, Xin Z, Sun Y, Li Y, Gao L, Xu Z, Bi J.   +8 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Bayesian Sample Size Calculations for External Validation Studies of Risk Prediction Models. [PDF]

Stat Med
Sadatsafavi M, Gustafson P, Setayeshgar S, Wynants L, D Riley R.   +4 more
europepmc   +1 more source

Sample size calculation practices in original research articles of the Journal of Conservative Dentistry and Endodontics (2021-2025). [PDF]

J Clin Exp Dent
Sánchez-Tito M.
europepmc   +1 more source

Estimating causal effects of rare treatments on binary outcomes: addressing sample size requirements and bias correction. [PDF]

BMC Med Res Methodol
Sanim AI, Rahman MS, Latif MAHM.
europepmc   +1 more source

Explainable IAOA-CNN-CBAM-SVR model for predicting air consumption of auxiliary nozzles with limited sample size. [PDF]

PLoS One
Shen M, Cao Y, Xiong X, Wang Z, Yu L, Yang X, Lv Y.   +6 more
europepmc   +1 more source

Impact of sample size of birds processed per pen in research settings for performance and quality data. [PDF]

Poult Sci
Maynard CJ, Thompson K, Mauromoustakos A, Owens CM.   +3 more
europepmc   +1 more source

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Nick Martin and the Genetics of Depression: Sample Size, Sample Size, Sample Size

Twin Research and Human Genetics, 2020
AbstractNick Martin is a pioneer in recognizing the need for large sample size to study the complex, heterogeneous and polygenic disorders of common mental disorders. In the predigital era, questionnaires were mailed to thousands of twin pairs around Australia. Always quick to adopt new technology, Nick’s studies progressed to phone interviews and then
Byrne, Enda M., Henders, Anjali K., Hickie, Ian B., Middeldorp, Christel M., Wray, Naomi R., Wray, Naomi R.   +5 more
openaire   +6 more sources

Sample Size

Archives of Pediatrics & Adolescent Medicine, 1988
Before undertaking a research comparison, investigators may wish to estimate the sample sizes needed to assure that the research is feasible and is worth the effort and expense. Such calculations require several decisions by the researchers: (1) the acceptable level of the type I error (P value), (2) the desired power of the test, (3) the difference ...
openaire   +2 more sources