Results 61 to 70 of about 4,409,426 (307)

Sample size calculation

open access: yesAllergologia et Immunopathologia, 2014
When designing any research project, definition is required of the sample size needed in order to carry out the study. This sample size is an estimate of the number of patients required in accordance with the pursued study objective. In this context, it is more efficient in terms of both cost and time to use samples than to work with the entire ...
Mm, Rodríguez Del Águila   +1 more
openaire   +2 more sources

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Sample Size Considerations for Hierarchical Populations [PDF]

open access: yesEFSA Journal, 2013
In applied sciences in general, and in particular when dealing with animal health and welfare assessments, one is often confronted with the collection of correlated data (not independent data).
European Food Safety Authority
doaj   +1 more source

Estimation of the two-group pilot sample size with a cautionary note on Browne’s formula

open access: yes, 2021
Using data obtained from a pilot study, Browne (1995) proposed a procedure for estimating the sample size needed for a definitive two-arm randomised controlled trial when the minimal important difference is specified. Simulations confirm these findings.
Toher, Deirdre   +2 more
core  

kkmann/unplanned-sample-size-adaptation 0.3.0

open access: yes, 2020
No description ...
Kevin Kunzmann
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

kkmann/sample-size-calculation-under-uncertainty 0.2.0

open access: yes, 2020
initial arxiv.org ...
Kevin Kunzmann
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Sample size determination algorithm for fingerprint-based indoor localization systems

open access: yes, 2016
Provision of accurate location information is an important task in the Internet of Things (IoT) applications and scenarios. This need has boosted the research and development of fingerprint based, indoor localization systems, since GPS information is not
Liotta, A.   +14 more
core   +1 more source

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