Results 41 to 50 of about 4,030,855 (263)
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
Basic Statistical Concepts for Sample Size Estimation
For grant proposals the investigator has to include an estimation of sample size .The size of the sample should be adequate enough so that there is sufficient data to reliably answer the research question being addressed by the study.
Vithal K Dhulkhed +4 more
doaj
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
Estimating Sample Size with Weibull Failure [PDF]
In censored type I samples, the total number n of individuals may be unknown. If the parent distribution is exponential Marcus-Blumenthal (1975) estimated n using Bayesian and non-Bayesian approaches.
S.K. Ashour, O.A. Shalaby
doaj +1 more source
An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos +2 more
wiley +1 more source
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
This paper sets forth the basic concepts of the calculation of sample size and power in clinical research. It provides the reader with a basic understanding of the relationship between sample size and power and the components within the research, such as the variability of the measure being used as the primary outcome. The paper also discusses a number
openaire +2 more sources
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla +6 more
wiley +1 more source
Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex +13 more
wiley +1 more source
Basic principles of sample size calculation
The calculation of sample size helps a medical researcher to assess cost, time, and feasibility of his project besides scientific justification and validity. Although frequently reported in journals, the details or the elements of sample size calculation
Shivam Pandey
doaj +1 more source

