Results 41 to 50 of about 4,030,855 (263)

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge   +6 more
wiley   +1 more source

Basic Statistical Concepts for Sample Size Estimation

open access: yesIndian Journal of Anaesthesia, 2008
For grant proposals the investigator has to include an estimation of sample size .The size of the sample should be adequate enough so that there is sufficient data to reliably answer the research question being addressed by the study.
Vithal K Dhulkhed   +4 more
doaj  

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

Estimating Sample Size with Weibull Failure [PDF]

open access: yesThe Egyptian Statistical Journal, 1979
In censored type I samples, the total number n of individuals may be unknown. If the parent distribution is exponential Marcus-Blumenthal (1975) estimated n using Bayesian and non-Bayesian approaches.
S.K. Ashour, O.A. Shalaby
doaj   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos   +2 more
wiley   +1 more source

Psychosocial Functioning After Pediatric Bone Sarcoma: Generic and Survivor‐Specific Outcomes in Adolescent and Young Adult Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek   +14 more
wiley   +1 more source

Sample Size and Power

open access: yesJournal of Investigative Surgery, 1993
This paper sets forth the basic concepts of the calculation of sample size and power in clinical research. It provides the reader with a basic understanding of the relationship between sample size and power and the components within the research, such as the variability of the measure being used as the primary outcome. The paper also discusses a number
openaire   +2 more sources

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla   +6 more
wiley   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex   +13 more
wiley   +1 more source

Basic principles of sample size calculation

open access: yesJournal of the Practice of Cardiovascular Sciences, 2020
The calculation of sample size helps a medical researcher to assess cost, time, and feasibility of his project besides scientific justification and validity. Although frequently reported in journals, the details or the elements of sample size calculation
Shivam Pandey
doaj   +1 more source

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