Results 71 to 80 of about 8,421,143 (315)
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Principles of sample size calculation
Indian Journal of Ophthalmology, 2010 In most areas in life, it is difficult to work with populations and hence researchers work with samples. The calculation of the sample size needed depends on the data type and distribution.
Gogtay Nithya
doaj
How sample size influences research outcomes
Dental Press Journal of Orthodontics, 2014 Sample size calculation is part of the early stages of conducting an epidemiological, clinical or lab study. In preparing a scientific paper, there are ethical and methodological indications for its use.
Jorge Faber, Lilian Martins Fonseca
doaj +1 more source
Basics of statistics-3: Sample size calculation – (i)
Cancer Research, Statistics, and Treatment, 2020 Introduction: From a practicing oncologist's perspective, sample size calculation is a very intriguing aspect of medical statistics. Methods: Basic aspects of sample size calculation in relevant case scenarios are discussed.
H S Darling
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Sample Size Determination to Evaluate the Impact of Highway Improvements [PDF]
, 1989 This paper was prepared for the Department of Transport, as a support document to a main report on the feasibility of measuring responses to highway improvements.
Fowkes, A.S., Watson, S.M.
core
Sample size and positive false discovery rate control for multiple testing
, 2007 The positive false discovery rate (pFDR) is a useful overall measure of errors for multiple hypothesis testing, especially when the underlying goal is to attain one or more discoveries. Control of pFDR critically depends on how much evidence is available
Chi, Zhiyi
core +3 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Sample size analysis for conducting research [PDF]
ITM Web of ConferencesThe paper describes a method for analyzing a sample size for conducting research. The main stages of sample size analysis with different error rates are considered. The stages of the work in the software for calculating the error rate and sample size are
Pokushko Mariia +5 more
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