Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
SMALL SAMPLE SIZE IN 2X2 CROSS OVER DESIGNS: CONDITIONS OF DETERMINATION
Journal of Research in Medical Sciences, 2001 Introduction. Determination of small sample size in some clinical trials is a matter of importance. In cross-over studies which are one types of clinical trials, the matter is more significant.
B SOLEYMANI +3 more
doaj
Effect of shape and size of sampling window on the determination of average length, intensity and density of trace discontinuity [PDF]
, 2016 A. Kamali +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Sampling Methods and Sample Size Determination in Clinical Research: An Educational Review
Journal of General and Family MedicineClinical research validity depends critically on sound sampling methodology and adequate sample size determination, yet many published studies demonstrate deficiencies in these fundamental aspects.
Azzam Zrineh +2 more
doaj +1 more source
Determination of Sample Size for Validation of Allergen-Screening Methods [PDF]
, 2003 Foster D McClure, Qian F Graves
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Sample size determination for external pilot cluster randomised trials with binary feasibility outcomes: a tutorial. [PDF]
Pilot Feasibility Stud, 2023 Hemming K +3 more
europepmc +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Practical approaches to Bayesian sample size determination in non-inferiority trials with binary outcomes. [PDF]
Stat Med, 2023 Turner RM +8 more
europepmc +1 more source