Results 141 to 150 of about 1,497,290 (270)
Sample Size Determination Using the Stratification Algorithms with the Occurrence of Stratum Jumpers [PDF]
Taekyong Hong, Jihun Ahn, Pyong Namkung
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This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
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Determination of sample size for various study designs in medical research: A practical primer
Formulating a research question and selecting an appropriate study design for answering that question are crucial initial steps in the research process.
Reena Bhardwaj+3 more
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Principles of cryometric impurity determination as applied to samples of small sizes
Charles Proffer Saylor, Gaylon S. Ross
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The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
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Quantifying experience in sample size determination for drug analysis of seized drugs [PDF]
Anders Nordgaard
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
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Introduction Longitudinal study designs are common in a lot of scientific researches, especially in medical, social and economic sciences. The reason is that longitudinal studies allow researchers to measure changes of each individual over time and often
Taban Baghfalaki
doaj
A Bayesian Method of Sample Size Determination with Practical Applications [PDF]
Sujit K. Sahu, T. M. F. Smith
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The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
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