Results 151 to 160 of about 3,758,239 (336)
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Sample size determination and evaluation for two-stage adaptive designs of single arm clinical trials based on median event time test. [PDF]
Park Y, Chen Y.
europepmc +1 more source
Two-Stage Design Sample Size Determination for Two Doses in Oncology Phase II Trials [PDF]
Meiruo Xiang, Yangruijue Ma, Qian Li
openalex +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
There is a particular importance of determining a basic minimum required 'n' size of the sample to recognize a particular measurement of a particular population. This article has highlighted the determination of an appropriate size to estimate population parameters.
openaire +3 more sources
SAMPLE SIZE DETERMINATION IN NON-RADOMIZED SURVIVAL STUDIES WITH NON-CENSORED AND CENSORED DATA
Introduction: In survival analysis, determination of sufficient sample size to achieve suitable statistical power is important .In both parametric and non-parametric methods of classic statistics, randomn selection of samples is a basic condition ...
S FAGHIHZADEH, M RAHGOZAR
doaj
Bayesian sample size determination for diagnostic accuracy studies. [PDF]
Wilson KJ +5 more
europepmc +1 more source
General purpose computer program for interacting supersonic configurations. User's manual [PDF]
The input data required to execute the computer program ISCON are described. The program generates a numerical procedure for the determination of unsteady aerodynamic forces on arbitrarily interacting wings and tails in supersonic flow.
Crill, W., Dale, B.
core +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source

