Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Biological and technical variability in mouse microbiota analysis and implications for sample size determination. [PDF]
Lab Anim (NY)McAdams Z, Gustafson K, Ericsson A.
europepmc +1 more source
Sample size determination for interval estimation of the prevalence of a sensitive attribute under non‐randomized response models [PDF]
Shi‐Fang Qiu +5 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Bayesian sample size determination for longitudinal intervention studies with linear and log-linear growth. [PDF]
Behav Res MethodsLösener U, Moerbeek M.
europepmc +1 more source
Remote, real-time expert elicitation to determine the prior probability distribution for Bayesian sample size determination in international randomised controlled trials: Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone (BIPED) study. [PDF]
Trials, 2022 Lan J +6 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
On Sample Size Determination for Augmented Tests Based on Restricted Mean Survival Time in Randomized Clinical Trials. [PDF]
Biom JHattori S, Uno H.
europepmc +1 more source
Determination of Soil Sample Size Based on Gy's Particulate Sampling Theory [PDF]
, 2011 Bumhan Bae
openalex +1 more source