Results 71 to 80 of about 1,497,290 (270)

Sample size determination for estimating antibody seroconversion rate under stable malaria transmission intensity [PDF]

open access: yes, 2015
Background In the last decade, several epidemiological studies have demonstrated the potential of using seroprevalence (SP) and seroconversion rate (SCR) as informative indicators of malaria burden in low transmission settings or in populations on the ...
Drakeley, C, Sepúlveda, N
core   +3 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Sample Size Determination and Power [PDF]

open access: yesInternational Statistical Review, 2015
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/111133/1/insr12095_8 ...
openaire   +3 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Pointwise estimate of the power and sample size determination for permutation tets

open access: yesStatistica, 2007
A method is presented for the estimation of the power of permutation tests when F is unknown. It is based on the natural plug-in of the empirical distribution in the structure of the statistical test, giving the bootstrap power.
Daniele De Martini
doaj   +1 more source

Laser Spectroscopic Measurement of Helium Isotope Ratios

open access: yes, 2003
A sensitive laser spectroscopic method has been applied to the quantitative determination of the isotope ratio of helium at the level of 3He/4He = 10^-7 - 10^-5.
Bjoklund   +24 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

The Effect of Linkage on Sample Size Determination for Multiple Trait Selection [PDF]

open access: yes, 1992
32 pages, 1 article*The Effect of Linkage on Sample Size Determination for Multiple Trait Selection* (Schwager, Steven J.; Mutschler, Martha A.; Federer, Walter T.; Scully, Brian T.) 32 ...
Cornell University. Biometrics Unit.   +6 more
core  

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