Embedded-deep-learning-based sample-to-answer device for on-site malaria diagnosis [PDF]
Improvements in digital microscopy are critical for the development of a malaria diagnosis method that is accurate at the cellular level and exhibits satisfactory clinical performance.
Chae Yun Bae +18 more
doaj +2 more sources
Sample-to-answer direct real-time PCR detection of Anaplasma phagocytophilum, Ehrlichia spp., and Babesia spp. infections in whole-blood specimens [PDF]
Emerging tick-borne illnesses, such as anaplasmosis, babesiosis, or ehrlichiosis, are caused by obligate intracellular pathogens that have clinically comparable presentations.
Georgia Colasante +3 more
doaj +2 more sources
A fully integrated sample-to-answer diagnostic platform enables rapid quantification of post-transplant infection at the point-of-care [PDF]
Opportunistic infections after organ transplantation require frequent monitoring over years. However, current diagnostic tests are inaccessible to patients in resource-limited settings.
Pengkun Yin +8 more
doaj +2 more sources
Detection of clinically relevant Candida species from positive blood cultures using a novel sample-to-answer molecular assay [PDF]
We evaluated the diagnostic performance of the newly developed MoiM Dx Candida 9-plex (MoiM) assay for the detection of Candida species from positive blood cultures and compared the results with those obtained from the BIOFIRE Blood Culture ...
Bosung Park +8 more
doaj +2 more sources
Detection of SARS-CoV-2 VOC-Omicron using commercial sample-to-answer real-time RT-PCR platforms and melting curve-based SNP assays [PDF]
Summary: Objectives: The World Health Organization (WHO) had designated the SARS-CoV-2 lineage B.1.1.529 as the new Variant of Concern Omicron (VOC-Omicron) on 26th November 20211.
Brian H.M. Sit +9 more
doaj +2 more sources
Sample-to-answer, extraction-free, real-time RT-LAMP test for SARS-CoV-2 in nasopharyngeal, nasal, and saliva samples: Implications and use for surveillance testing [PDF]
The global COVID-19 pandemic has highlighted the need for rapid, accurate and accessible nucleic acid tests to enable timely identification of infected individuals. We optimized a sample-to-answer nucleic acid test for SARS-CoV-2 that provides results in
Kathryn A. Kundrod +13 more
doaj +3 more sources
Correction: A fully automated sample-to-answer PCR system for easy and sensitive detection of dengue virus in human serum and mosquitos. [PDF]
[This corrects the article DOI: 10.1371/journal.pone.0218139.].
PLOS ONE Staff
doaj +2 more sources
Demonstration of a fast and easy sample-to-answer protocol for tuberculosis screening in point-of-care settings: A proof of concept study. [PDF]
We sought to develop a smooth and low cost sample preparation and DNA extraction protocol, streamlined with a ready-to-use qPCR in a portable instrument to overcome some of the existing hurdles.
Nasir Ali +4 more
doaj +2 more sources
Sample-to-Answer Robotic ELISA. [PDF]
Enzyme-linked immunosorbent assays (ELISA), as one of the most used immunoassays, have been conducted ubiquitously in hospitals, research laboratories, etc.
Zhou C +7 more
europepmc +2 more sources
Sample–to-answer sensing technologies for nucleic acid preparation and detection in the field
Efficient sample preparation and accurate disease diagnosis under field conditions are of great importance for the early intervention of diseases in humans, animals, and plants.
Chia-Wei Liu, Hideaki Tsutsui
doaj +1 more source

