Results 121 to 130 of about 13,047,740 (287)

Fitted parameter values (best fitting sample for each coherence).

open access: yes, 2015
Fitted parameter values (best fitting sample for each coherence).
Stefan J. Kiebel (191755)   +2 more
core   +1 more source

Handgrip strength reference values and dynapenia risk thresholds in an urban adult sample from Lima, Peru

open access: yesFrontiers in Rehabilitation Sciences
BackgroundHandgrip strength is widely recognized as a practical biomarker of muscle function and an important screening tool for sarcopenia and functional decline. However, most di-agnostic thresholds currently used in clinical practice were developed in
Santos Lucio Chero-Pisfil   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Comparison of sample preparation methods for higher heating values in various sugarcane varieties using near-infrared spectroscopy

open access: yesSmart Agricultural Technology
This study developed an efficient system for measuring the energy characteristics of energy canes in breeding programs using near-infrared spectroscopy with the aim of significantly improving the accuracy of selecting high-performing sugarcane clones.
Kantisa Phoomwarin   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Variance stabilized gene expression data and p-values

open access: yes, 2015
Variance stabilized gene expression and p-values were generated using the R package DESeq2. Row names are gene names. Column names are either sample names (columns 1-24) or p-values (columns 25-30).
Mikhail V. Matz (51701)   +7 more
core   +1 more source

Development and evaluation of a whole-chain management system for critical value reporting

open access: yesBMC Medical Informatics and Decision Making
Background Critical value (CV) management is vital for patient safety and shows the quality of critical care. This study aimed to develop a whole-chain management system (WCMS) for CV reporting and evaluate its impact on clinical practice. Methods A WCMS
Dongdong Wu   +7 more
doaj   +1 more source

Small Samples’ Permille Cramér–Von Mises Statistic Critical Values for Continuous Distributions as Functions of Sample Size

open access: yesData
Along with other order statistics, the Cramér–von Mises (CM) statistic can assess the goodness of fit. CM does not have an explicit formula for the cumulative distribution function and the alternate way is to obtain its critical value from a Monte Carlo (
Lorentz Jäntschi
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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