Results 121 to 130 of about 13,047,740 (287)
Fitted parameter values (best fitting sample for each coherence).
Fitted parameter values (best fitting sample for each coherence).
Stefan J. Kiebel (191755) +2 more
core +1 more source
BackgroundHandgrip strength is widely recognized as a practical biomarker of muscle function and an important screening tool for sarcopenia and functional decline. However, most di-agnostic thresholds currently used in clinical practice were developed in
Santos Lucio Chero-Pisfil +8 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
This study developed an efficient system for measuring the energy characteristics of energy canes in breeding programs using near-infrared spectroscopy with the aim of significantly improving the accuracy of selecting high-performing sugarcane clones.
Kantisa Phoomwarin +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Variance stabilized gene expression data and p-values
Variance stabilized gene expression and p-values were generated using the R package DESeq2. Row names are gene names. Column names are either sample names (columns 1-24) or p-values (columns 25-30).
Mikhail V. Matz (51701) +7 more
core +1 more source
Development and evaluation of a whole-chain management system for critical value reporting
Background Critical value (CV) management is vital for patient safety and shows the quality of critical care. This study aimed to develop a whole-chain management system (WCMS) for CV reporting and evaluate its impact on clinical practice. Methods A WCMS
Dongdong Wu +7 more
doaj +1 more source
Along with other order statistics, the Cramér–von Mises (CM) statistic can assess the goodness of fit. CM does not have an explicit formula for the cumulative distribution function and the alternate way is to obtain its critical value from a Monte Carlo (
Lorentz Jäntschi
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

