Results 131 to 140 of about 13,047,740 (287)

Basic Human Values in the Swiss Population and in a Sample of Farmers

open access: yes, 2011
Basic human values were investigated in Swiss farmers. The main objective was to take a first step toward elucidating the structure and profile of basic human values in farmers.
Dobricki, Martin, Martin Dobricki
core   +1 more source

The analysis of stability and variability of metrological characteristic (conversion coefficient) of glass capillary reference viscometers

open access: yesОмский научный вестник
The results of determining the stability and variability of the main characteristic of glass capillary reference viscometers — conversion coefficient — by analyzing a set of data on viscometers having different diameters of the measuring capillary are ...
V. Sh. Sulaberidze, A. A. Neklyudova
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Multivariate out-of-sample tests for Granger causality. [PDF]

open access: yes
A time series is said to Granger cause another series if it has incremental predictive power when forecasting it. While Granger causality tests have been studied extensively in the univariate setting, much less is known for the multivariate case. In this
Croux, Christophe, Gelper, Sarah
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Prediction of finite population totals based on the sample distribution

open access: yes, 2003
This article studies the use of the sample distribution for the prediction of finite population totals under single-stage sampling. The proposed predictors employ the sample values of the target study variable, the sampling weights of the sample units ...
Sverchkov, Michail, Pfeffermann, Danny
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Gene ranking by bootstrapped P-values

open access: yes, 2003
Recent research has shown that it is possible to find genes involved in the pathogenesis of a particular condition on the basis of microarray experiments.
SN Mukherjee (21867206)   +3 more
core   +3 more sources

Home - About - Disclaimer - Privacy