Results 121 to 130 of about 7,760,600 (326)

Scientific drilling of speleothems – a technical note

open access: yesInternational Journal of Speleology, 2012
This short article provides detailed descriptions of custom-made and commercially available hand-held drilling gear and options for water-flushing units specifically designed to obtained good-quality core material from speleothems even in remote cave ...
Spötl Christoph, Mattey David
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Sampling Individually Fundamental Simplexes as Sets of Players’ Mixed Strategies in Finite Noncooperative Game for Applicable Approximate Nash Equilibrium Situations with Possible Concessions

open access: yesJournal of Information and Organizational Sciences, 2016
In finite noncooperative game, a method for finding approximate Nash equilibrium situations is developed. The method is prior-based on sampling fundamental simplexes being the sets of players’ mixed strategies. Whereas the sampling is exercised, the sets
Vadim V. Romanuke
doaj  

Recolección de muestras de pudrición basal de las palmas causada por Ganoderma

open access: yesEDIS
Las palmeras son una parte integral del paisaje urbano de Florida. La pudrición de las palmas por Ganoderma, una enfermedad causada por el hongo Ganoderma zonatum, que descompone la madera, es una de las principales preocupaciones bióticas para la ...
Braham Dhillon , Seemanti Chakrabarti
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Statistical distribution sampling [PDF]

open access: yes
Determining the distribution of statistics by sampling was investigated. Characteristic functions, the quadratic regression problem, and the differential equations for the characteristic functions are ...
Johnson, E. S.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy