Results 81 to 90 of about 2,070,030 (304)

The effects of weighting in the regression analysis of survey data collected using non-probabilistic sampling methods: A secondary data analysis

open access: yes, 2019
Introduction When surveys are conducted especially for hidden populations, data is rarely collected using random sampling which is the ideal way to collect representative data.
Mudadi, Leon-Say
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Using data from camera traps and autonomous recording units to evaluate and improve species-habitat inferences

open access: yesAvian Conservation and Ecology
In vast and remote regions such as the boreal forest of northern Canada, population dynamics of most wildlife species are poorly understood because of limited sampling.
Laura N. Stewart   +8 more
doaj   +1 more source

Improved sampling algorithm for stochastic modelling of random-wound electrical machines

open access: yesThe Journal of Engineering, 2019
Random-wound electrical machines often suffer from high circulating current losses. These losses vary from machine to machine in a stochastic fashion. This study proposes an improved sampling algorithm for quantifying the uncertainty inherent in random ...
Antti Lehikoinen   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The effects of weighting in the regression analysis of survey data collected using non-probabilistic sampling methods: A secondary data analysis

open access: yes, 2017
Introduction When surveys are conducted especially for hidden populations, data is rarely collected using random sampling which is the ideal way to collect representative data.
Mudadi, Leon-Say
core  

Jump-Diffusion Langevin Dynamics for Multimodal Posterior Sampling

open access: yes, 2023
reservedBayesian methods of sampling from a posterior distribution are becoming increasingly popular due to their ability to precisely display the uncertainty of a model fit.
GUIDOLIN, JACOPO
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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