Results 91 to 100 of about 261,559 (305)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Enhanced Digital Signal Processing of Signal-dependently Sampled Data
Asynchronous circuits receive now an increasing interest. Their promising advantages can play a significant role in future electronics' development. One of the factors, which delay the wide spread of the clock-less systems, is incompatibility with classical clock-driven analog to digital converters and processing algorithms.
M. Greitāns, I. Homjakovs
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Acquisition times and storage requirements have become increasingly important in signal-processing applications, as the sizes of datasets have increased.
Yisak Kim, Juyoung Park, Hyungsuk Kim
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Wavefield modeling and signal processing for sensor arrays of arbitrary geometry [PDF]
Sensor arrays and related signal processing methods are key technologies in many areas of engineering including wireless communication systems, radar and sonar as well as in biomedical applications.
Costa, Mário Jorge
core
All-optical sampling utilising two-photon absorption in semiconductor microcavity [PDF]
A highly-efficient optical sampling system based on Two-Photon Absorption in a semiconductor micro-cavity is presented.
Krug, T. +14 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
We present experimentally a low-complexity ultralow switching energy and high-linearity all-optical sampling gate based on a terahertz optical asymmetric demultiplexer, constructed by placing a polarization-insensitive multiple-quantum-well semiconductor
P. Li +4 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

